Results 191 to 200 of about 14,055 (218)

Translation and Replication of FMDV RNA

2005
Foot-and-mouth disease virus (FMDV) RNA is infectious. After delivery of the RNA (about 8.3 kb) into the cytoplasm of a cell, the RNA must initially be translated to produce the viral proteins required for RNA replication and for the packaging of the RNA into new virions. Subsequently there has to be a switch in the function of the RNA; translation has
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Swine TRIM21 restricts FMDV infection via an intracellular neutralization mechanism

Antiviral Research, 2016
The tripartite motif protein 21 (TRIM21) is a ubiquitously expressed E3 ubiquitin ligase and an intracellular antibody receptor. TRIM21 mediates antibody-dependent intracellular neutralization (ADIN) in cytosol and provides an intracellular immune response to protect host defense against pathogen infection.
Wenchun, Fan, Dong, Zhang, Ping, Qian, Suhong, Qian, Mengge, Wu, Huanchun, Chen, Xiangmin, Li   +6 more
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Vaccines prepared from chimeras of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies and protective immunity to multiple serotypes of FMDV

Journal of Virology, 1994
The G-H loop of VP1 (residues 132 to 159) of foot-and-mouth disease virus (FMDV) is a prominent feature on the virion surface and has an important role in vaccine efficacy, generation of antigenic variants, and cell binding. Using an infectious cDNA of FMDV, we have constructed serotype A viruses in which the G-H loop has been substituted with the ...
E, Rieder, B, Baxt, J, Lubroth, P W, Mason   +3 more
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Transcriptomic analysis of porcine PBMCs in response to FMDV infection

Acta Tropica, 2017
Foot-and-mouth disease (FMD) is a significant zoonotic infectious disease. It has an important economic impact throughout the world. As well, it is a considerable threat to food security. At present, the molecular mechanism of FMDV infection is not clear to a large extent. Innate immune response is the first line of defense against infectious diseases.
Fu-Rong, Zhao, Yin-Li, Xie, Ze-Zhong, Liu, Jun-Jun, Shao, Shi-Fang, Li, Yong-Guang, Zhang, Hui-Yun, Chang   +6 more
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Modification of FMDV anti-host defense mechanism [PDF]

, 2014
Foot-and-mouth disease virus (FMDV) is the etiologic agent of FMD, an infectious and sometimes fatal viral disease that affects cloven-hoofed animals. The FMDV genome encodes a large polyprotein, the first component of which is the Leader protein. Unusually, within the picornavirus family, the FMDV Leader protein (Lpro) is a protease.
Guan, Suhua, Belsham, Graham
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Detection of FMDV RNA amplified by the polymerase chain reaction (PCR)

Journal of Virological Methods, 1992
Molecular detection of foot-and-mouth disease virus (FMDV) using the polymerase chain reaction (PCR) is a rapid and accurate method. In this study we present PCR for the detection of FMDV RNA in infected BHK cells. Using PCR and two primers selected from the RNA polymerase gene, a conserved sequence in all types and subtypes of FMDV, we were able to ...
O, Laor, H, Torgersen, H, Yadin, Y, Becker   +3 more
exaly   +3 more sources

High selectivity detection of FMDV- SAT-2 using a newly-developed electrochemical nanosensors

Biosensors and Bioelectronics, 2021
Heba Ahmed Hussein, Rasha Mohamed El Nashar, Ibrahim M El-Sherbiny   +2 more
exaly  

Some aspects of FMDV-production in growing cells and a closed system for concentration of FMDV by polyethylene glycol.

Developments in biological standardization, 1979
Different commercially available peptone preparations, all derived by enzymatic digestion of meat, were tested for their ability to replace the individual amino acids and polyethylene glycol (PEG)-treated serum in BHK suspended cell culture growth medium.
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Natural Phytochemicals, Luteolin and Isoginkgetin, Inhibit 3C Protease and Infection of FMDV, In Silico and In Vitro

Viruses, 2021
Sirin Theerawatanasirikul, Chih-Jung Kuo, Ploypailin Semkum   +2 more
exaly  

Investigating the quaternary structure of the FMDV Leader protease

2009
Das Maul-und Klauenseuchevirus (MKSV) stellt ein Mitglied der Picornavirus-Familie dar und ist ein kleines, nicht-umhülltes Virus mit einem einzelsträngigen RNA-Genom mit positiver Polarität. Das RNA-Genom wird direkt in ein Polyprotein translatiert, welches anschließend von viralen Proteasen prozessiert wird.
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