Results 81 to 90 of about 4,585,382 (236)

β3-Adrenoceptor activation upregulates apolipoprotein A-I expression in HepG2 cells, which might further promote cholesterol efflux from macrophage foam cells

Drug Design, Development and Therapy, 2017
Xia-qing Gao,1,2 Yan-fang Li,1,2 Zhi-li Jiang1,2 1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 2Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People’s Republic of China Objective: The aim ...
Gao XQ, Li YF, Jiang ZL
doaj  

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines [PDF]

, 2006
Objective - Although inflammation is a recognized feature of atherosclerosis, the impact of inflammation on cellular cholesterol homeostasis is unclear.
Moorhead, JF, Wheeler, DC, Ruan, XZ, Varghese, Z, Ma, KL, Tao, JL, Powis, SH   +6 more
core  

Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation

iMetaOmics
Foam cells derived from macrophages and smooth muscle cells (SMCs) play a pivotal role in the progression of atherosclerosis. While phytosterols (PS) have demonstrated cholesterol‐lowering and anti‐inflammatory properties, their impact on foam cells ...
Baiyi Lu, Fan Xiao, Qinjun Zhang, Yao Xie, Mengmeng Wang, Jesus Simal‐Gandara, Yan Liu, Thomas Efferth, Weisu Huang, Jianfu Shen, Jianbo Xiao   +10 more
doaj   +1 more source

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

Advanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer, H. Mutlu, C. Charmette, E. Randrianaridera, Z. Adaidi, R. Hedna, L. Pieuchot, I. Pluvy, K. Anselme, N. Couturier, J. P. Mericq, A. Ponche, I. Brigaud   +12 more
wiley   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Foam extrusion behavior and correlation between foam morphology and foam properties of externally plasticized cellulose acetate using inert gases

, 2022
S.213-218Today, polystyrene (PS) and polypropylene (PP) are the standard polymers for producing extruded foam sheets for packaging. Basically, these polymers are based on non-renewable resources and are non-biodegradable.
Berdel, K., Kabasci, S., Radusch, H.J., Hildebrand, T., Luck, F. van, Wodke, Thomas, Zepnik, S.   +6 more
core   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Pathogenic mycobacterium upregulates cholesterol 25-hydroxylase to promote granuloma development via foam cell formation

iScience
Summary: Pathogenic mycobacteria orchestrate the complex cell populations known as granuloma that is the hallmark of tuberculosis. Foam cells, a lipid-rich cell-type, are considered critical for granuloma formation; however, the causative factor in foam ...
Shuang Zhou, Ding Zhang, Dan Li, Hankun Wang, Cairong Ding, Jingrui Song, Weifeng Huang, Xuan Xia, Ziwei Zhou, Shanshan Han, Zhu Jin, Bo Yan, Jacqueline Gonzales, Laura E. Via, Lu Zhang, Decheng Wang   +15 more
doaj   +1 more source

Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities

Advanced Materials, EarlyView.
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen, Zhanxi Fan, Jingjie Ge, Qiyuan He, Zhuangchai Lai, Jiawei Liu, Chaoliang Tan, Hua Zhang   +7 more
wiley   +1 more source