Results 191 to 200 of about 50,276 (321)

Beyond mTOR: Unraveling the Complex Pathophysiology and Signaling Pathways in Focal Cortical Dysplasia. [PDF]

Mol Neurobiol
Yang K, He Y, Leng J, Lu T, Wang Y, Xie K, Song T, Zhong C, Zhang L.   +8 more
europepmc   +1 more source

Diagnostic Yield of Sequencing for Prenatal Diagnosis of Fetal Structural Anomalies: An Updated Systematic Review

Prenatal Diagnosis, EarlyView.
ABSTRACT The clinical utility of sequencing in prenatal diagnosis is known, but diagnostic yield varies widely depending on clinical indication. Here we update an earlier systematic review reporting the diagnostic yield of prenatal sequencing in structurally abnormal fetuses, with particular focus on factors affecting diagnostic yield.
Karen Mei Xian Lim, Alexander Gibbs, Elizabeth Scotchman, Graeme Smith, Lyn S. Chitty, Natalie J. Chandler   +5 more
wiley   +1 more source

Pseudo-healthy image synthesis via location-guided diffusion models for focal cortical dysplasia lesion localization. [PDF]

Sci Rep
Li Y, Pan Y, Zhang X, Liu Q, Wang C, Ge R.   +5 more
europepmc   +1 more source

Neuropathologic findings and age‐related differences in Finnish pediatric medico‐legal autopsies

Journal of Forensic Sciences, EarlyView.
Abstract Neuropathological examination plays a critical role in medico‐legal cause‐of‐death investigation, especially in determining the cause and manner of death in pediatric autopsies. Although a comprehensive neuropathological examination is recommended, limited data exists of the diagnostic yield of neuropathology consultations in such cases.
Elias Hakanen, Petteri Oura, Paula Katriina Vauhkonen   +2 more
wiley   +1 more source

Lesionectomy as management for super-refractory status epilepticus due to focal cortical dysplasia: illustrative case. [PDF]

J Neurosurg Case Lessons
Gonzalez-Salido J, Fuentes-Calvo I, Martinez-Medina S, Colado-Martinez J, Marin-Castañeda LA, Robles-Lomelin P, Cienfuegos-Meza J, Díaz-Martínez R, Ramos-Sanchez RJ, Vasquez-Lopez F, Vázquez-Cruz BC, Vera López JC, Salgado-Deza M, Alcala-Romero C, Vázquez-Hernández OI, Santizo-Nanduca I, Moreno Avellán Á, Ferndandez-Gonzalez-Aragon M, Arellano-Reynoso A, Sebastián-Díaz MA, Cruz-Pérez J, Tena Suck ML, Martínez-Juárez IE.   +22 more
europepmc   +1 more source

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

Brain Pathology, EarlyView.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu, Yanan Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Alterations in dopaminergic innervation and receptors in focal cortical dysplasia. [PDF]

Brain
Meli N, Sheran K, Pitsch J, Krabbe S, Borger V, Baumgartner T, Becker A, Blaess S.   +7 more
europepmc   +1 more source

Comparing thalamic volumes between focal cortical dysplasia patients and healthy individuals. [PDF]

Am J Neurodegener Dis
Bahrami M, Hekmatnia A, Mehvari-Habibabadi J, Sourani A, Ramezani N, Azizollahi S.   +5 more
europepmc   +1 more source

Surfaced-based detection of focal cortical dysplasia using magnetic resonance fingerprinting and machine learning. [PDF]

Epilepsia
Su TY, Hu S, Wang X, Adler S, Wagstyl K, Ding Z, Choi JY, Sakaie K, Blümcke I, Murakami H, Alexopoulos AV, Jones SE, Najm I, Ma D, Wang ZI.   +14 more
europepmc   +1 more source

Artificial intelligence‐based statistical modeling delineates architectural distortion in focal cortical dysplasia

Brain Pathology, EarlyView.
Histopathological identification of subtle cortical architectural abnormalities in focal cortical dysplasia (FCD) resections remains challenging. We investigated if artificial intelligence (AI)‐based morphometric and spatial analysis of NeuN‐stained cortical sections could detect neuronal architectural disorganization in epilepsy resections, including ...
Andrew Cannon, Roland Tian, Blake Ebner, Robert E. Watson Jr., Brian Burkett, Jamie Van Gompel, Lily C. Wong‐Kisiel, Christopher P. Hartley, Roger K. Moreira, Aditya Raghunathan   +9 more
wiley   +1 more source