Results 121 to 130 of about 90,457 (326)

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source

Manifestaciones metafocales de infección odontógena y su relación directa con oftalmopatías Metafocal manifestations of odontogenic infection and their direct relationship with ophthalmopathies

Medisan, 2009
La infección focal se caracteriza por la presencia de un foco séptico primario, que puede localizarse en la región bucofacial e irradiarse a otras partes distales o sistémicas, lo cual impone diagnosticarla adecuada y oportunamente para poder tratarla y ...
José Manuel Díaz Fernández, José Jardón Caballero, Ricardo Pérez Arredondo   +2 more
doaj  

Single‐Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein‐Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as
Zengqing Liu, Xiaoxia Ren, Mi Mu, Huanyu Long, Jialu Lv, Zhihong Feng, Jie Liu, Jiajia Wang, Hui Deng, Fanyu Shi, Muzhi Zhang, Ruoyang Zhang, Yang Liu, Mengyu Xu, Yang Fan, Zengtao Wang, Zhe Lv, Yan Chen, Chris J. Corrigan, Ying Sun, Yahong Chen, Chen Chen, Ye Cui, Wei Wang   +23 more
wiley   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Impacto social de la estrategia para disminuir la incidencia de celulitis facial odontógena: Matanzas Social impact of the strategy to determine the incidence of odontogenic facial cellulites: Matanzas

Revista Médica Electrónica, 2009
La celulitis facial odontógena es relativamente frecuente, puede convertirse en un grave riesgo vital cuando el tratamiento no es adecuado. Su incidencia es un problema de salud, demuestra que las medidas y acciones de promoción y prevención de salud no ...
María Teresa Lima Reyna
doaj  

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

Advanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao, Zhilei Wang, Pengchang Zheng, Jingyu Xie, Yangzhen Wang, Yun Chen, Zilin Wang, Ao Li, Minghuan Wang, Quanbo Ji, Can Gao, Di Yao, Lingbo Li, Jiangbei Cao   +13 more
wiley   +1 more source

[Dental focal infection. Literature review].

Fogorvosi szemle, 2003
The author gives an account of the history of the dental foci from the ancient times up to the present day, together with the change of the concept of dental foci and their modern interpretation. The article points out the shift in the assessment of the importance of focal infection.
openaire   +1 more source

Role of Dentists in Prescribing Opioid Analgesics and Antibiotics: An Overview [PDF]

, 2018
Ackerman, Al-Huwayrini, Aldous, Aminoshariae, Amir Azarpazhooh, Ashrafioun, Baker, Baur, Bax, Birrenbach, Bohnert, Budnitz, Cabana, Cadieux, Center for Disease Control and Prevention, Christopher Okunseri, Conly, Cooper, Crane, Cunha, Dar-Odeh, De-Bem, Denisco, Dionne, Dirks, Dodd, Dowell, Drekonja, Ellison, European Centre for Disease Prevention and Control (CDC), Fazakerley, Fleming-Dutra, Forbes, Gonzales, Gordon, Grimshaw, Grol, Guy, Haas, Hasegawa, Hicks, Irvine, John, Kakoei, Katie J. Suda, Katz, Kumar, Lam, Levy, Lewis, Little, Logan, Longman, Ma, Martin, McCauley, Mutlu, Nima Laghapour, Ong, Ostini, Pallasch, Pallasch, Pallasch, Palmer, Palmer, Paluck, Paulozzi, Porucznik, Pynn, Ralph Dana, Rasubala, Rigoni, Rodriguez-Nunez, Runciman, Saadat, Samaranayake, Sawair, Schumock, Seager, Segura-Egea, Shehab, Smith, Spurling, Steed, Steinmetz, Substance Abuse and Mental Health Services Administration, Suda, Sweeney, Thornhill, Thornhill, Tufts Health Care Institute, Van der Sanden, Vanderweil, Vessal, Volkow, Wall, Wang, Wright, Yingling, Zimmerman   +99 more
core   +2 more sources