Results 51 to 60 of about 321,758 (264)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Focal Mechanism and Parameter of Volcano-Tectonic Earthquake Source, in Mount Guntur, West Java

open access: yesIndonesian Journal on Geoscience, 2014
DOI: 10.17014/ijog.v6i1.111Guntur Volcano in West Java is one of the most active volcanoes in Indonesia. The last eruption took place in 1847 and the volcanic activity has been dormant since then, however its seismicity is active.
Sri Hidayati, Y. Suparman, A. Loeqman
doaj   +1 more source

Study on tectonic stress field in Yingjiang area based on multi-focal mechanism solution sequence

open access: yes地震科学进展, 2021
In this paper,a total of 162 focal mechanism solutions are collected from several focal mechanism solution sequences in Yingjiang area,and the tectonic stress field inversion is carried out from Sudian fault to Dayingjiang fault.
Bing Feng   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Focal mechanisms in anisotropic media [PDF]

open access: yesGeophysical Journal International, 2005
SUMMARY Focal mechanisms of seismic sources in anisotropic media are more complicated than in isotropic media. Planar shear faulting produces pure double-couple (DC) mechanism in isotropy, but generally non-double-couple (non-DC) mechanism in anisotropy.
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Seismic characteristics of the 15 February 2013 bolide explosion in Chelyabinsk, Russia

open access: yesEarth and Planetary Physics, 2018
The seismological characteristics of the 15 February 2013 Chelyabinsk bolide explosion are investigated based on seismograms recorded at 50 stations with epicentral distances ranging from 229 to 4324 km.
Zhi Wei   +4 more
doaj   +1 more source

2019年黄海ML4.6地震序列的震源机制和发震构造

open access: yesDizhen xuebao, 2020
2019年黄海ML4.6地震序列发生在NW向苏北—滨海断裂带附近,历史上该断裂带附近曾多次发生破坏性地震。为了判断此次地震序列的发生是否与苏北—滨海断裂带活动有关,本文基于黄海ML4.6地震震中附近400 km范围内的测震台站记录,采用CAP方法计算了此次黄海地震序列中ML4.6和ML4.1地震的深度和震源机制解参数,并使用双差定位方法对该地震序列进行了重新定位。研究结果显示:2019年12月8日黄海ML4.6和12日黄海ML4.1地震的震源深度分别为20 km和21 km,位于发震区域的脆韧转换带内 ...
Yingchun Li   +4 more
doaj   +1 more source

Dynamics and Mechanism of p130Cas Localization to Focal Adhesions [PDF]

open access: yesJournal of Biological Chemistry, 2010
The docking protein p130Cas is a major Src substrate involved in integrin signaling and mechanotransduction. Tyrosine phosphorylation of p130Cas in focal adhesions (FAs) has been linked to enhanced cell migration, invasion, proliferation, and survival.
Dominique M, Donato   +4 more
openaire   +2 more sources

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