Results 71 to 80 of about 4,240,767 (303)

Dynamics and Mechanism of p130Cas Localization to Focal Adhesions [PDF]

Journal of Biological Chemistry, 2010
The docking protein p130Cas is a major Src substrate involved in integrin signaling and mechanotransduction. Tyrosine phosphorylation of p130Cas in focal adhesions (FAs) has been linked to enhanced cell migration, invasion, proliferation, and survival.
Dominique M, Donato, Larisa M, Ryzhova, Leslie M, Meenderink, Irina, Kaverina, Steven K, Hanks   +4 more
openaire   +2 more sources

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Study on the attenuation relationship of the acceleration envelope parameters for the Wenchuan earthquake aftershocks

Frontiers in Earth Science
The seismic attenuation relationship between ground motion parameters (such as peak acceleration and response spectra value) and seismic parameters (such as magnitude and epicentral distance) is an important foundation for seismic hazard analysis and the
Deyu Yin
doaj   +1 more source

Molecular Mechanisms of Proteinuria in Focal Segmental Glomerulosclerosis [PDF]

Frontiers in Medicine, 2018
Focal segmental glomerulosclerosis (FSGS) is the most common primary glomerular disease resulting in end-stage renal disease in the USA and is increasing in prevalence worldwide. It is a diverse clinical entity with idiopathic, genetic, metabolic, infectious, and other causes that culminate in a characteristic histologic pattern of injury.
Yumeng Wen, Sapna Shah, Kirk N. Campbell
openaire   +3 more sources

Representation of Sickle Cell Disease Patients in Pediatric and Adult Care: What We Discovered Using Informatics for Integrating Biology and the Bedside (i2b2) Data

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth, Kholod Alhassan, Ada De La Osa, John Stephen, Yue Yao, Diana J. Wilkie   +5 more
wiley   +1 more source

REFMC 1929 - 2012 (Romanian Earthquake Focal Mechanism Catalogue)

, 2020
REFMC 1929 - 2012 (Romanian Earthquake Focal Mechanism Catalogue) was compiled by Mircea Radulian, Andrei Bălă and Dragoș Toma-Dănilă from the National Institute for Earth Physics (INFP), Romania (http://www.infp.ro/) and comprises of earthquakes in ...
Radulian, M (via Mendeley Data), Toma-Danila, Dragos   +1 more
core   +1 more source

FocoNet: Transformer‐Based Focal‐Mechanism Determination

Journal of Geophysical Research: Machine Learning and Computation
Traditional focal‐mechanism determination primarily relies on fitting the first‐motion polarities with grid‐search algorithms. We developed a machine‐learning model, FocoNet, to include more seismic information into focal mechanism determination.
Xiaohan Song, Men‐Andrin Meier, William L. Ellsworth, Gregory C. Beroza   +3 more
doaj   +1 more source

Rapid report of source parameters of 2023 M6.2 Jishishan, Gansu earthquake sequence

Earth and Planetary Physics
The M6.2 earthquake in Jishishan, Gansu Province, on December 18, 2023, caused extraordinary earthquake disasters. It was located in the northern part of the north−south seismic zone, which is a key area for earthquake monitoring in China.
ZhiGao Yang, Jie Liu, YingYing Zhang, Wen Yang, XueMei Zhang   +4 more
doaj   +1 more source

Mechanisms of Disease Reversal in Focal and Segmental Glomerulosclerosis [PDF]

Advances in Chronic Kidney Disease, 2014
It is well known that progression of chronic kidney disease can be ameliorated or stabilized by different interventions, but more studies indicate that it can even be reversed. Most data suggest that current therapy, especially renin-angiotensin system inhibition alone, is not sufficient to initiate and maintain long-term regression of glomerular ...
Hai-Chun Yang, Agnes B. Fogo
openaire   +2 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source