Results 71 to 80 of about 321,758 (264)

Rapid report of source parameters of 2023 M6.2 Jishishan, Gansu earthquake sequence

Earth and Planetary Physics
The M6.2 earthquake in Jishishan, Gansu Province, on December 18, 2023, caused extraordinary earthquake disasters. It was located in the northern part of the north−south seismic zone, which is a key area for earthquake monitoring in China.
ZhiGao Yang, Jie Liu, YingYing Zhang, Wen Yang, XueMei Zhang   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Role of Fluids in Fault Mechanics: A 16‐Year Analysis of the Irpinia Seismicity (Southern Italy)

Geophysical Research Letters
Fluids in the crust influence earthquake nucleation by affecting fault strength and rupture dynamics, but direct observations at seismogenic depths are rare.
G. M. Adinolfi, F. Guiñez‐Rivas, J. Campos, R. De Matteis   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

SEISMICITY AND CRUSTAL SEISMOTECTONIC DEFORMATIONS OF THE ANATOLIAN PLATE (TURKEY)

Геодинамика и тектонофизика
The paper deals with the study of seismicity and the crustal stress-strain state of Turkey whose tectonics is caused by relative movements of the African, Aegean, Arabian, Anatolian, Black Sea and Eurasian plates.
N. А. Sycheva
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Rupture process of the 2023 MW 6.1 Jishishan (China) earthquake in a compressional stress regime and implications for seismic hazards

Geomatics, Natural Hazards & Risk
On 18 December 2023, an MW 6.1 earthquake struck Jishishan County, China, and occurred on a blind thrust fault at the northeastern edge of the Tibetan Plateau.
Xiangyun Guo, Xu Zhang, Xinxin Yin, Lei Yi, Anjian Wang, Chaoyong Peng, Shiguang Wang, Bo Zhang, Long Zhang, Zhenyue Li   +9 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source