Results 31 to 40 of about 345,336 (263)
Mechanism of Focal Adhesion Kinase Mechanosensing
PLOS Computational Biology, 2015 Mechanosensing at focal adhesions regulates vital cellular processes. Here, we present results from molecular dynamics (MD) and mechano-biochemical network simulations that suggest a direct role of Focal Adhesion Kinase (FAK) as a mechano-sensor. Tensile forces, propagating from the membrane through the PIP2 binding site of the FERM domain and from the
Jing Zhou +5 more
openaire +6 more sources
An Automatic Workflow to Infer Focal Mechanisms of Microearthquakes: Application to Southern Italy
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingThe focal mechanism of an earthquake is a key element to constrain the slipping fault and the stress field. Despite that, its calculation may be very challenging in the case of small-magnitude earthquakes because of the difficulty in determining the ...
Mauro Palo +4 more
doaj +1 more source
Focal mechanism determination for voIcanic microearthquakes
Annals of Geophysics, 1994 Classical methods to infer focal mechanisms from first P wave motions are of limited use for the analysis of small magnitude events occurring in volcanic areas, due to structure complexity.
G. De Natale
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The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
GeoHazardsThe analysis of earthquake source mechanisms is key for seismotectonic studies, but it is often limited to traditional methods plagued with issues of precision and automation.
Francisca Guiñez-Rivas +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Frontiers in Earth ScienceThe seismotectonics of the Northwestern (NW) Ethiopian plateau and the adjacent rift flanks were studied using local earthquake data recorded by broadband seismic networks.
Sisay Alemayehu +3 more
doaj +1 more source
A note on Northern Marche seismicity: new focal mechanisms and seismological evidence
Annals of Geophysics, 2003 A geodynamic interpretation of the Northern Marche region is diffi cult, the zone being characterized by complex structures which cannot be defi ned in the form of a simple, standard model.
S. Santini
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source