Results 91 to 100 of about 80,952 (305)

Ketogenic Diet in Refractory Focal Seizures

, 2001
The efficacy of the ketogenic diet in the treatment of intractable focal seizures was studied retrospectively in 34 patients (mean age, 7.5 yrs; range, 4 months to 29 yrs) and compared to 100 patients with generalized seizures at the Cleveland Clinic ...
J Gordon Millichap
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Hemispheric differences in the duration of focal onset seizures [PDF]

, 2020
OBJECTIVE To assess hemispheric differences in the duration of focal onset seizures and its association with clinical and demographic factors. METHODS A retrospective analysis was performed on adult patients with drug-resistant unifocal epilepsy, who
Vollmar, Christian, Seethaler, Magdalena, Lauseker, Michael, Ernst, Katharina, Rémi, Jan, Noachtar, Soheyl, Kaufmann, Elisabeth   +6 more
core   +1 more source

A unique case of nontraumatic femoral neck fracture following epilepsia partialis continua

Epilepsy and Behavior Case Reports, 2015
People with epilepsy are more accident prone than the non-epilepsy population. Bone fractures are most often due to seizure-related falls. However, seizures themselves, in particular generalized tonic-clonic seizures, may also cause fractures, e.g.
Karl O. Nakken
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Tract-specific atrophy in focal epilepsy: Disease, genetics, or seizures? [PDF]

, 2017
OBJECTIVE: To investigate whether genetics, underlying pathology, or repeated seizures contribute to atrophy in specific white matter tracts. METHODS: Medically refractory unilateral temporal lobe epilepsy (TLE) with hippocampal sclerosis (HS-TLE, n = 26)
Tsai, MH, Connelly, A, Vaughan, David N., Tsai, Meng Han, Vaughan, DN, Tournier, JD, Curwood, Evan, Tournier, Jacques Donald, Raffelt, David, Jackson, Graeme D., Jackson, GD, Raffelt, D, Connelly, Alan, Curwood, E   +13 more
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Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Simultaneous intracranial EEG and fMRI of interictal epileptic discharges in humans [PDF]

, 2011
Simultaneous scalp EEG–fMRI measurements allow the study of epileptic networks and more generally, of the coupling between neuronal activity and haemodynamic changes in the brain.
Walker, M.C., Lemieux, L., Rodionov, R., McEvoy, A.W., Matthew C. Walker, Karin Rosenkranz, Rosenkranz, K., Serge Vulliemoz, David W. Carmichael, Beate Diehl, Louis Lemieux, Carmichael, D.W., Diehl, B., Vulliemoz, S., Roman Rodionov, Andrew W. McEvoy   +15 more
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Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Association mapping of genomic microdeletions and common susceptibility variants predisposing to genetic generalized epilepsies

, 2013
Approximately 3% of the general population is affected by epilepsy during lifetime, making epilepsy one of the most common neurological diseases. Genetic generalized epilepsies (GGE) are the most common of genetic epilepsies and account for 20-30% of ...
Trucks, Holger Sebastian
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