Results 101 to 110 of about 511,553 (294)

Focal nonconvulsive seizures during detoxification for benzodiazepine abuse.

, 2012
Chronic benzodiazepine (BDZ) abuse is currently treated with detoxification using a low-dose flumazenil infusion, a relatively recently developed and promising procedure.
Quaglio G., Faccini M., FIASCHI, Antonio, Lugoboni F., BONGIOVANNI, Luigi Giuseppe, BRIGO, Francesco, ALBIERO, Anna, Casari R., Storti M.   +8 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Movement disorders phenomenology in focal motor seizures

, 2018
Introduction: Although focal motor seizures may resemble one or more movement disorders their phenomenology and prevalence remain uncertain. Methods: To examine the extent to which focal motor seizures can present with a phenomenology fulfilling ...
Di Gennaro, Giancarlo, Defazio G, Fabbrini G., Iorio, Raffaele, Fabbrini, Giovanni, Borlot, Felipe, Di Bonaventura C, Fasano, Alfonso, Andrade D, Striano P., Espay, Alberto J., Fasano A, Bove F., Andrade, Danielle, Di Bonaventura, Carlo, Bui E, Espay AJ, Fabbrini G, Luigetti M., Di Gennaro G., Munhoz R. P., Defazio, Giovanni, Andrade D., Borlot F, Fasano A., Defazio G., Luigetti, Marco, Morgante, Francesca, Katzberg H., Morgante F, BOVE, FRANCESCO, Bui E., Di Bonaventura C., Borlot F., Luigetti M, Katzberg, Hans, Striano, Pasquale, Iorio R3, Bui, Esther, Morgante F., Iorio R., Di Gennaro G, Munhoz RP, Berardelli, Alfredo, Espay A. J., Striano P, Katzberg H, Bove F, Munhoz, Renato P., Berardelli A.   +49 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Seizure frequency can be reduced by changing intracranial pressure: A case report in drug-resistant epilepsy

Epilepsy and Behavior Case Reports, 2018
A relationship between seizures and intracranial pressure (ICP) has been proposed, but not clearly identified. Whether changes in ICP can evoke seizures remains controversial.
Daiki Uchida, Ayataka Fujimoto, Tomohiro Yamazoe, Takamichi Yamamoto, Hideo Enoki   +4 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

An iEEG investigation on sex‐specific differences in seizure duration

Epilepsia Open
Objective Male people with epilepsy (mPWE) are at higher risk for bilateral tonic–clonic seizures (BTCs) and sudden unexpected death in epilepsy (SUDEP) compared to female people with epilepsy (fPWE).
Paula Albert I Gracenea, Alexandra Muss, Magdalena Seethaler, Jan Rémi, Elisabeth Kaufmann   +4 more
doaj   +1 more source

The spectrum of first-onset seizures in children presenting at a tertiary care centre

Advances in Human Biology
Introduction: Seizure is the most common paediatric neurological condition with an increased predilection for early childhood. The recent definition of epilepsy includes first-onset seizures with an increased probability of future episodes.
Venkata Sai K Chagantipati, Utkarsh Bansal, Ekansh Rathoria, Vijay Singh, Nyay Bhai Gupta, Ravindra Ahuja   +5 more
doaj   +1 more source