Results 101 to 110 of about 80,952 (305)
Intracerebral temperature alterations associated with focal seizures
, 2002 Because focal seizures produce an increase in local cerebral metabolism and blood flow, we wanted to determine whether they might lead to changes in brain temperature. We induced focal neocortical seizures by microinjection of 4-aminopyridine (4-AP) into
장종희
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Analysis of Focal Seizures with CT Correlation [PDF]
, 2008 INTRODUCTION: As early as 400 B.C. when Hippocrates wrote about epilepsy till the present day when medical sciences have reached the heights of sophistication with various investigations like Computed Tomography, Magnetic Resonance Imaging and Positron ...
Uma Maheswari, E
core
Precipitation and inhibition of seizures in focal epilepsies
, 2018 Introduction: There is growing awareness that reflex epileptic seizures offer unique insight into natural seizure generation in humans. In the last years, focus has mostly been on reflex seizures in generalized epilepsies whereas a comprehensive review ...
Rūta Mameniškienė +3 more
core +1 more source
Epilepsy and Behavior Case Reports, 2018 A relationship between seizures and intracranial pressure (ICP) has been proposed, but not clearly identified. Whether changes in ICP can evoke seizures remains controversial.
Daiki Uchida +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Seizures, Focal EEG Abnormalities, and CT
, 1993 The prevalence and nature of abnormalities on CT associated with focal EEG abnormalities were evaluated in 964 consecutive children with epileptic and non-epileptic seizures seen over one year at the Royal Liverpool Children’s Hospital ...
J Gordon Millichap
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An iEEG investigation on sex‐specific differences in seizure duration
Epilepsia OpenObjective Male people with epilepsy (mPWE) are at higher risk for bilateral tonic–clonic seizures (BTCs) and sudden unexpected death in epilepsy (SUDEP) compared to female people with epilepsy (fPWE).
Paula Albert I Gracenea +4 more
doaj +1 more source