Results 81 to 90 of about 7,641,705 (256)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

MRI-guided Focal Treatment of Prostate Cancer. [PDF]

Radiol Imaging Cancer, 2021
Liu X.
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Lipid nitroalkene nanoparticles for the focal treatment of ischemia reperfusion. [PDF]

Nanotheranostics, 2022
Yu GZ, Ramasamy T, Fazzari M, Chen X, Freeman B, Pacella JJ.   +5 more
europepmc   +1 more source

Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]

, 2007
Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition ...
Candelario-Jalil, Eduardo, Fiebich, Bernd L., Gonzalez-Falcon, Armando, Fiebich, Bernd, Garcia-Cabrera, Michel, Leon, Olga Sonia   +5 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluación del tratamiento focal contra el Aedes aegypti en áreas de salud seleccionadas de Ciudad de La Habana, junio del 2008

Revista Cubana de Higiene y Epidemiología
El tratamiento focal es considerado el pilar fundamental de la vigilancia y lucha contra el Aedes (Stegomya) aegypti, mediante el cual se detecta y destruye el mosquito en sus fases pre-adultas, además de educarse sanitariamente a la población.
Vivian Noriega Bravo, Isora Ramos Valle, Yanett Morejón Díaz, Roberto Molina Torriente   +3 more
doaj  

Self-Assembling Imageable Silk Hydrogels for the Focal Treatment of Osteosarcoma. [PDF]

Front Cell Dev Biol, 2022
Peng Z, Li M, Wang Y, Yang H, Wei W, Liang M, Shi J, Liu R, Li R, Zhang Y, Liu J, Shi X, Wan R, Fu Y, Xie R, Wang Y.   +15 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Available evidence on HIFU for focal treatment of prostate cancer: a systematic review. [PDF]

Int Braz J Urol, 2022
Bakavicius A, Marra G, Macek P, Robertson C, Abreu AL, George AK, Malavaud B, Coloby P, Rischmann P, Moschini M, Rastinehad AR, Sidana A, Stabile A, Tourinho-Barbosa R, de la Rosette J, Ahmed H, Polascik T, Cathelineau X, Sanchez-Salas R.   +18 more
europepmc   +1 more source