Results 191 to 200 of about 14,099,511 (342)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

What happened and what proves you wrong? Combatting confirmation bias in police investigations through evidence reconstruction and falsification. [PDF]

PLoS One
Lenz S, Zohrevand T, Rassin E, Verschuere B.   +3 more
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Conversation Barriers and Strategies Used by People With Parkinson's and Their Partners to Support Conversation. [PDF]

Int J Lang Commun Disord
Thilakaratne R, Wylie K, Loftus AM, Cocks N.   +3 more
europepmc   +1 more source

A Study on the Effect of Beauty Service of the Elderly on Successful Ageing: Focused on Mediated Effect of Self-esteem [PDF]

, 2018
Myung-Hee Jung, Moon Ji-Sun
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Temporal pulse shaping aspects of refractive X-ray lenses. [PDF]

J Synchrotron Radiat
Trost F, Bielecki J, Bean R.
europepmc   +1 more source

Effectiveness of Solution- Focused Brief Therapy (SFBT) on Reducing Depression and Increasing Marital Satisfaction in Married Women [PDF]

, 2017
Amin Abbasi, Massood Mohammadi, Kianoush Zahrakar, Reza Davarniya, M Babaeigarmkhani   +4 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Quantitative Assessment of Focus Quality in Whole-Slide Imaging of Thyroid Liquid-Based Cytology Using Laplacian Variance. [PDF]

Endocr Pathol
Jung CK, Kim C, Jeon S, Bychkov A.
europepmc   +1 more source