Results 121 to 130 of about 6,559,079 (294)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Focus Groups on Infant Care Practices in Missouri [PDF]

open access: yes, 2005
The goal of this research project was to better understand how individuals, primarily low-income African-American parents in Missouri, make decisions on infant care practices, specifically those focused around feeding and ...
Mosley, Jane M.   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

‘Unfocused groups’: lessons learnt amid remote focus groups in the Philippines

open access: yesFamily Medicine and Community Health, 2021
Mark Donald C Reñosa   +8 more
doaj   +1 more source

COMBINING TASTE PANELS WITH FOCUS GROUPS TO ELICIT CONSUMER PREFERENCES TOWARD A NEW SHRIMP PRODUCT [PDF]

open access: yes
Consumer/Household Economics,
Davis, Kathy J.   +3 more
core   +1 more source

Health Trainers End of Year Review 1st April 2013 – 31st March 2014 [PDF]

open access: yes, 2014
A critical assessment of health trainer activity, with particular reference to the most deprived social groups, and a focus on mental health and ...
Bagnall, A, Trigwell, J, White, J
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

What's Trust Got To Do With It? [PDF]

open access: yes, 2011
Based on focus groups with parents, explores why school turnaround options such as closing failing schools and replacing principals and staff provoke community opposition.

core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Our Voice Is Your Future: Giving L.A.'s Youth Real Voice and Real Power [PDF]

open access: yes, 2004
Based on focus groups with youth and youth workers, identifies best practices and opportunities to engage youth in community-building.

core  

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