Results 131 to 140 of about 6,504,407 (344)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

‘Unfocused groups’: lessons learnt amid remote focus groups in the Philippines

open access: yesFamily Medicine and Community Health, 2021
Mark Donald C Reñosa   +8 more
doaj   +1 more source

Challenges in communicating the benefits of switching from cigarettes to e-cigarettes: Responses from eight adult focus groups with varying smoking experience

open access: gold, 2022
Rosemary J. Avery   +7 more
openalex   +1 more source

Focus groups, community engagement, and researching with young people [PDF]

open access: yes, 2017
Over the last decade, participatory action research (PAR) has been increasingly used in geography in an attempt to move away from identifying and theorizing problems towards engaging with social action, impact and empowering local communities ...
Lloyd-Evans, Sally
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Usefulness of the patient information leaflet (PIL) and information on medicines from professionals: A patients’ view. A qualitative study

open access: yesZdravniški Vestnik, 2014
Background: The Patient information leaflet (PIL) is an important source of information for every patient. Little is known about whether patients read the PIL and whether it contains useful information.
Tonka Poplas-Susič   +2 more
doaj  

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