Results 191 to 200 of about 6,504,407 (344)

Understanding overdose risk and response in permanent supportive housing: results of focus groups with tenants, staff, and leaders. [PDF]

Addict Sci Clin Pract
Gaeta Gazzola M, Torsiglieri A, Blaufarb S, Velez L, Hernandez P, O'Grady MA, Shelley D, Frank D, Cleland CM, Doran KM.   +9 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Promoting Independence of People with Intellectual Disabilities: A Focus Group Study Perspectives from People with Intellectual Disabilities, Legal Representatives, and Support Staff [PDF]

, 2018
Janice Sandjojo, Winifred A. Gebhardt, A.M.E.E. Zedlitz, Joop Hoekman, Jeanet A. den Haan, Andrea W.M. Evers   +5 more
openalex   +1 more source

Protocol for an undergraduate student-led scoping review of methods used to conduct inclusive focus groups with autistic adolescents. [PDF]

PLoS One
Medum N, Stocker T, Finkler M, Hellín López J, Edwards N, Sommers M, Gaston M, Johnson EM, Schadler A, Byars J, Griese J, Campos-Castillo C.   +11 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Iconography of Vehicle Automation – A Focus Group Study

, 2021
Joy Richardson, Kirsten M. A. Revell, Jisun Kim, Neville A. Stanton   +3 more
openalex   +2 more sources

Challenges of Joint Crisis Plans with Migrant Patients: Focus Groups with Mental Health Professionals and Interpreters. [PDF]

Community Ment Health J
Weber O, Semlali I, Wenger V, Ferrari P, Mota SF, Almeida SR, Brodard A, Dutray F.   +7 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Morphofunctional Profile Focusing on Strength and Ultrasound of the Upper Limbs in Female Breast Cancer Survivors: A Comparative Cross-Sectional Study Between Groups with and Without Lymphoedema and Between Ipsilateral and Contralateral Limbs [PDF]

Ana Rafaela Cardozo da Silva, Juliana Netto Maia, Vanessa Maria da Silva Alves Gomes, Naiany Tenório de Jesus, Juliana Fernandes, Ana Claúdia Souza da Silva, Vanessa Patrícia Soares de Sousa, Leila Barbosa, Armèle Dornelas de Andrade, Diego de Sousa Dantas   +9 more
openalex   +1 more source

Adoption of Focus Groups in Designing Interventions to Address Vaccine Hesitancy Among Adolescents and Their Parents: A Systematic Review. [PDF]

Vaccines (Basel)
Calella P, Pelullo CP, Di Giuseppe G, Napolitano F, Liguori F, Liguori G, Gallè F.   +6 more
europepmc   +1 more source