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MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases
Science Translational Medicine, 2021Description MRgFUS is a safe, noninvasive method to deliver spatially targeted monoclonal antibody across the BBB in patients with brain tumors. Focusing on delivery Drug delivery to the brain is hampered by the presence of the blood-brain barrier (BBB).
Y. Meng +16 more
semanticscholar +1 more source
Bilateral Focused Ultrasound Thalamotomy for Essential Tremor (BEST‐FUS Phase 2 Trial)
Movement Disorders, 2021In patients with medically refractory essential tremor, unilateral magnetic resonance–guided focused ultrasound thalamotomy can improve contralateral tremor. However, this procedure does not address ipsilateral symptoms.
C. Iorio-Morin +17 more
semanticscholar +1 more source
Focused ultrasound: focused on tremor
Expert Review of Medical DevicesIntroduction Magnetic resonance-guided focused ultrasound (MRgFUS) has emerged as a leading noninvasive therapy for tremor, offering a precise, lesion-based alternative to deep brain stimulation (DBS) and traditional lesioning techniques. By using phased
Benjamin Davidson, Andres M. Lozano
semanticscholar +1 more source
Uterine Myomas: Focused Ultrasound Surgery.
Seminars in ultrasound, CT, and MR, 2021Uterine fibroids are the most common neoplasm in women. These lesions may be associated with impaired fertility and adverse obstetric outcomes. Medical treatment, myomectomy, hysterectomy and uterine artery embolization have been employed for the ...
A. Napoli +6 more
semanticscholar +1 more source
Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Nature Reviews Neurology, 2020Y. Meng, K. Hynynen, N. Lipsman
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