Results 111 to 120 of about 199,110 (278)

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

Evaluating the association of depressive symptoms on serum folate and erythrocyte folate levels based on the 2017–2020 NHANES database

Frontiers in Nutrition
ObjectiveTo improve further the management of the nutritional status and dietary habits of depressed patients.MethodsThis study investigated the effect of different severity states of depressive symptoms on serum and erythrocyte folate levels using the ...
Yunhong Yang, Huaqian Qi, Jiahao Zhang, Jie Jia, Yunsong Yang, Hong Zhao   +5 more
doaj   +1 more source

Infant Serum and Maternal Milk Vitamin B-12 Are Positively Correlated in Kenyan Infant-Mother Dyads at 1-6 Months Postpartum, Irrespective of Infant Feeding Practice. [PDF]

, 2018
BackgroundVitamin B-12 is an essential nutrient required for many functions including DNA synthesis, erythropoiesis, and brain development. If maternal milk vitamin B-12 concentrations are low, infants may face elevated risks of deficiency when ...
Achando, Beryl, Allen, Lindsay H, Chantry, Caroline J, Hampel, Daniela, Kiprotich, Marion, Lin, Audrie, Null, Clair A, Shahab-Ferdows, Setareh, Stewart, Christine P, Williams, Anne M   +9 more
core   +3 more sources

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Genome and transcriptome wide association study identify candidate genes regulating folate levels in maize

Frontiers in Plant Science
BackgroundMaize (Zea mays L.) serves as a crucial dietary source of folate for humans. However, the genetic regulatory mechanisms underlying the natural variation of folate in maize remain poorly understood.
Chenglin Zou, Meng Yang, Aihua Huang, Runxiu Mo, Ruining Zhai, Kaijian Huang   +5 more
doaj   +1 more source

Folate Measurement in Mammalian Tissues by Fluorescence Polarization

Pteridines, 2011
Measurement of folate in animal tissues is expensive and time-consuming. A fluorescence polarization assay has been developed that allows the rapid and inexpensive quantification of folate in various animal tissues.
Harry Martin, Comeskey Daniel
doaj   +1 more source

Effect of folic acid supplementation in pregnancy on preeclampsia: The folic acid clinical trial study [PDF]

, 2013
Copyright © 2013 Shi Wu Wen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited ...
Champagne, J, Coyle, D, Fergusson, D, Fraser, W, Rennicks White, R, Smith, G, Walker, MC, Wen, SW   +7 more
core   +4 more sources

Impact of Dietary Folate Deficiency on Behavioral and Genetic Outcomes [PDF]

, 2019
Undergraduate ...
Lenz, Abigail, Upchurch, Britton, Xu, Feifan   +2 more
core   +1 more source

Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? [PDF]

, 2016
Background: Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis.
Bosch, Guido, Eeckhaut, Venessa, Hesta, Myriam, Janssens, Geert, Junius, Greet, Liu, Daisy, Niu, Yufeng, Ribeiro Alves Lourenço, Marta, Van de Maele, Isabel, Van de Wiele, Tom, Van Immerseel, Filip, Verbrugghe, Adronie, Wuyts, Brigitte, Xu, Jia   +13 more
core   +2 more sources

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

Animal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem, Samy A. Elsaadawy, Zhaohai Wu, Lu Ma, Todd R. Callaway, Dengpan Bu   +5 more
wiley   +1 more source