Results 51 to 60 of about 199,110 (278)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy [PDF]

, 2016
Background: The uremic milieu exposes chronic kidney disease (CKD) patients to premature ageing processes. The impact of renal replacement therapy (dialysis and renal transplantation [RTx]) or immunosuppressive treatment regimens on ageing biomarkers has
Bárány, Peter, Curley, Hannah, Genberg, Helena, Luttropp, Karin, McGuinness, Dagmara, Nordfors, Louise, Quasim, Tara, Qureshi, Abdul Rashid, Sandberg, John, Schalling, Martin, Shiels, Paul G., Stenvinkel, Peter, Sönnerborg, Isabella, Wennberg, Lars   +13 more
core   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Dependence of bioavailability of folic acid and (6S)-5-methyltetrahydrofolate on baseline red blood cell folate concentrations in infants

Human Nutrition & Metabolism
Background: Folate bioavailability may depend on folate status of an individual and the form of folate presents in foods. Objective: We studied whether changes of red blood cell (RBC)-folate concentrations following dietary intervention with folic acid ...
Rima Obeid, Ines Warnke, Christina Hecht, Barbara Troesch, Luisa Barbanti, Matteo Tanadini, Berthold Koletzko   +6 more
doaj   +1 more source

Folate Deficiency: Is it Related to the Development of Depression

Pakistan Armed Forces Medical Journal, 2023
Objectives: To determine the frequency of serum folate deficiency among patients with depression and to compare mean serum folate levels with the severity level of depression. Study Design: Cross-sectional study. Place and Duration of Study: Armed
Asif Azeem Bajwa, Sohail Ali, Sikandar Ali Khan, Hassan Raza, Fayyaz Hussain, Tashfeen Bin Nazir   +5 more
doaj   +1 more source

Effect of low-dosage vitamin A and riboflavin on iron-folate supplementation in anaemic pregnant women [PDF]

, 2002
A double-blind, placebo, controlled trial was conducted in Banyudono subdistrict, Boyolali regency, Central Java province, Indonesia. The aim of the study was to determine whether adding low-dosage vitamin A and riboflavin can enhance the effect of ...
Suhanantyo,, Suprapto, Bambang, Widardo,
core  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

The long-term impact of folic acid in pregnancy on offspring DNA methylation : follow-up of the Aberdeen folic acid supplementation trial (AFAST) [PDF]

, 2018
Funding This work was supported by the NIHR Bristol Biomedical Research Centre at the University Hospitals Bristol NHS Foundation Trust and the University of Bristol.
Atkinson, Charlotte, Bhattacharya, Sohinee, Campbell, Doris, Gaunt, Tom, Hall, Marion, Herbert, Georgia, Kazmi, Nabila, McArdle, Wendy, Ness, Andy, Relton, Caroline L., Richmond, Rebecca C., Ring, Susan, Sharp, Gemma C., Smith, George Davey, Taylor, Caroline   +14 more
core   +3 more sources

Rethinking Extracellular Vesicle Signaling

Advanced Materials, EarlyView.
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley   +1 more source

Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus

BMC Endocrine Disorders, 2023
Background Type 2 diabetes mellitus (T2DM) and thyroid dysfunction (TD) are two common chronic endocrine disorders that often coexist. Folate deficiency has been reported to be related with the onset and development of T2DM.
Lin Lin, Yushan Du, Guanyu Niu, Shuangbo Xia, Jufen Liu   +4 more
doaj   +1 more source