Results 41 to 50 of about 140,665 (287)
Background In 1998, mandatory folic acid fortification of white flour and select cereal grain products was implemented in Canada with the intention to increase dietary folate intakes of reproducing women.
Sherwood Kelly L +2 more
doaj +1 more source
Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]
: Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Moore, SE +4 more
core +5 more sources
Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine
Clinical studies suggest a relationship between folate deficiency and neurological and disorders including Alzheimer’s disease (AD). To investigate mechanisms underlying this association, we examined the consequences of folate deprivation on neuronal ...
Pei I Ho +6 more
doaj +1 more source
Do dietary patterns in older men influence change in homocysteine through folate fortification? The Normative Aging Study [PDF]
Objective We aimed to describe the difference in B-vitamin intake and in plasma B-vitamin and homocysteine concentrations before and after folic acid fortification, in relation to dietary patterns. Design The Normative Aging Study (NAS) is a longitudinal
Groot, C.P.G.M., de +5 more
core +1 more source
Folate and Inflammation – links between folate and features of inflammatory conditions
Folate serves as a cofactor for one-carbon (1C) transfer reactions. These reactions are involved in the synthesis of DNA nucleotides, the amino acid methionine, and in the regulation of homocysteine (Hcy) levels.
Patrice Jones +4 more
doaj +1 more source
The Manipulation of Folate Biosynthesis in Lactic Acid Bacteria with a Folate Analog and Enhancers
Folate biosynthesis in Lacticaseibacillus rhamnosus R23 isolate of breast milk and Limosilactobacillus fermentum JK13 isolate of kefir granules was manipulated by stressing them with a folate analog (methotrexate) to increase extracellular folate ...
Fenny Amilia Mahara +2 more
doaj +1 more source
Folate determination in livers of different animal species
The liver is the main storage organ for folate. In the study the folate content in chicken, turkey, pig, and beef livers was evaluated with the use of the HPLC (high performance liquid chromatography) method which allowed various folate vitamers ...
Marta Czarnowska-Kujawska +2 more
doaj +1 more source
One-third of the global population is affected by micronutrient deficiency, particularly folate. Although folate synthesis has been relatively well characterized, few folate-related genes in maize have been cloned, and the molecular mechanism regulating ...
Yanyan Jiao +13 more
doaj +1 more source
It is proven that folic acid supplied in the periconceptional period can lower the recurrence and occurrence rate of neural tube defects (NTDs). Our research team on prevention of birth defects could demonstrate that folic acid preventable NTDs are partly based on hyperhomocystinemia and a genetic predisposition (mutation of the ...
openaire +4 more sources
The Relationship Between Unmetabolized Folic Acid and Serum Folate Concentrations and Cancer Risk in Older US Adults [PDF]
THE RELATIONSHIP BETWEEN UNMETABOLIZED FOLIC ACID AND SERUM FOLATE CONCENTRATIONS AND CANCER RISK IN OLDER US ADULTS by Regine L. Baldauff Importance Several studies have reported an increase in serum and unmetabolized folic acid levels since the ...
Baldauff, Regine L
core +1 more source

