Results 21 to 30 of about 101,651 (261)

Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

open access: yesScientific Reports, 2017
Maternal folate deficiency is linked to restricted fetal growth, however the underlying mechanisms remain to be established. Here we tested the hypothesis that mTOR functions as a folate sensor in vivo in mice and that maternal folate deficiency inhibits
Fredrick J. Rosario   +3 more
doaj   +1 more source

How well do blood folate concentrations predict dietary folate intakes in a sample of Canadian lactating women exposed to high levels of folate? An observational study

open access: yesBMC Pregnancy and Childbirth, 2007
Background In 1998, mandatory folic acid fortification of white flour and select cereal grain products was implemented in Canada with the intention to increase dietary folate intakes of reproducing women.
Sherwood Kelly L   +2 more
doaj   +1 more source

Analysis of the mediating role of BMI in associations of different folate forms with hepatic steatosis and liver fibrosis in adolescents in the USA: results from the NHANES 2017-2018

open access: yesFrontiers in Endocrinology, 2023
BackgroundMost studies have explored the relationship between serum total folate and nonalcoholic fatty liver disease (NAFLD) in adults, but there has been no study on the relationship between different folate forms and hepatic steatosis or liver ...
Jingli Wen   +8 more
doaj   +1 more source

Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine

open access: yesNeurobiology of Disease, 2003
Clinical studies suggest a relationship between folate deficiency and neurological and disorders including Alzheimer’s disease (AD). To investigate mechanisms underlying this association, we examined the consequences of folate deprivation on neuronal ...
Pei I Ho   +6 more
doaj   +1 more source

Folate determination in livers of different animal species

open access: yesCzech Journal of Food Sciences, 2020
The liver is the main storage organ for folate. In the study the folate content in chicken, turkey, pig, and beef livers was evaluated with the use of the HPLC (high performance liquid chromatography) method which allowed various folate vitamers ...
Marta Czarnowska-Kujawska   +2 more
doaj   +1 more source

Folate and Inflammation – links between folate and features of inflammatory conditions

open access: yesJournal of Nutrition & Intermediary Metabolism, 2019
Folate serves as a cofactor for one-carbon (1C) transfer reactions. These reactions are involved in the synthesis of DNA nucleotides, the amino acid methionine, and in the regulation of homocysteine (Hcy) levels.
Patrice Jones   +4 more
doaj   +1 more source

Integrated transcriptomic and proteomic analysis identified key folate biosynthesis gene in waxy maize

open access: yesCrop Journal
One-third of the global population is affected by micronutrient deficiency, particularly folate. Although folate synthesis has been relatively well characterized, few folate-related genes in maize have been cloned, and the molecular mechanism regulating ...
Yanyan Jiao   +13 more
doaj   +1 more source

Folate (vitamin B9) content analysis in bread wheat (Triticum aestivum L.)

open access: yesFrontiers in Nutrition, 2022
Vitamin B9, particularly folic acid, is an essential molecule for human health. Wheat flour is one of the major sources of calorie intake by humans. The selection of folate-rich genotypes in wheat breeding can enhance the natural folate value in the ...
Jun Zheng   +7 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Identification of QTLs Underlying Folate Content in Milled Rice

open access: yesJournal of Integrative Agriculture, 2014
Understanding the genetic mechanism underlying folate biosynthesis and accumulation in rice would be beneficial for breeding high folate content varieties as a cost-effective approach to addressing widespread folate deficiency in developing countries. In
Wei DONG   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy