Results 1 to 10 of about 101,651 (261)

Folate as a Key Regulator of Animal Intestinal Homeostasis: From Metabolism to Microbiota and Barrier Function [PDF]

Animals
Folate is a central nutrient in one-carbon metabolism, contributing to nucleotide biosynthesis, methionine cycling, methyl-donor supply, and epigenetic regulation.
Yi Zheng, Yecheng Xu, Xin Wen, Xi Qiao, Tianzhao Yao, Linlin Wei, Huahua Du   +6 more
doaj   +2 more sources

Network Pharmacology Combined With Clinical Retrospective Analysis to Investigate the Potential Mechanisms and Clinical Significance of Folate in Treating Spinal Cord Injury [PDF]

Pharmacology Research & Perspectives
Folate is an indispensable nutrient involved in key biological processes, including enzymatic reactions, DNA replication, metabolic regulation, and methylation.
Xiaolei Chu, Jiajia Liang, Jiaojiao Sun, Wenjie Liu, Lei Zhang, Zheng Xing, Qingwen Li, Qi Li   +7 more
doaj   +2 more sources

Ischemia-Reperfusion Injury Reduces Kidney Folate Transporter Expression and Plasma Folate Levels

Frontiers in Immunology, 2021
Acute or chronic kidney disease can cause micronutrient deficiency. Patients with end-stage renal disease, kidney transplantation or on dialysis have reduced circulating levels of folate, an essential B vitamin.
Cheng Yang, Cheng Yang, Charith U. B. Wijerathne, Charith U. B. Wijerathne, Guo-wei Tu, Connie W. H. Woo, Yaw L. Siow, Yaw L. Siow, Yaw L. Siow, Susara Madduma Hewage, Susara Madduma Hewage, Kathy K. W. Au-Yeung, Kathy K. W. Au-Yeung, Tongyu Zhu, Tongyu Zhu, Karmin O, Karmin O, Karmin O   +17 more
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Folate Bioavailability [PDF]

Proceedings of the Nutrition Society, 2004
The achievement of optimal folate status to prevent neural-tube defects, and possibly other diseases, is hindered by the well-recognised incomplete bioavailability of the natural folates found in foods compared with the synthetic vitamin, folic acid.
Helene, McNulty, Kristina, Pentieva
openaire   +2 more sources

Formylation of Folate as a Step in Physiological Folate Absorption [PDF]

Clinical Science, 1973
Oral administration of folate analogues to rats is followed by a rise in plasma folate detectable only by micro-biological assay with Lactobacillus casei, suggesting methylation of folate during absorption. When using the everted rat gut technique with folate (PteGlu), dihydrofolate (H 2 ...
J, Perry, I, Chanarin
openaire   +3 more sources

Selection of the Parameters in the Synthesis of Ethylenediamine-Folate Using the Plackett Burman Design

Indonesian Journal of Chemistry, 2022
This study is concerned with synthesizing ethylenediamine-folate (EDA-Folate), which will then be used as a precursor in synthesizing Gd-PEG-DOTA-Folate, a novel targeted-contrast agent for the diagnosis of cancer, employing the Magnetic Resonance ...
Erianti Siska Purnamasari, Linda Septiana, Ari Hardianto, Ukun Mochammad Syukur Soedjanaatmadja, Anni Anggraeni, Husein Hernadi Bahti   +5 more
doaj   +1 more source

One crisis, diverse impacts-Tissue-specificity of folate deficiency-induced circulation defects in zebrafish larvae. [PDF]

PLoS ONE, 2017
Folate (vitamin B9) is an essential nutrient required for cell survival, proliferation, differentiation and therefore embryogenesis. Folate deficiency has been associated with many diseases, including congenital heart diseases and megaloblastic anemia ...
Hung-Chi Tu, Gang-Hui Lee, Tsun-Hsien Hsiao, Tseng-Ting Kao, Tzu-Ya Wang, Jen-Ning Tsai, Tzu-Fun Fu   +6 more
doaj   +1 more source

Folate Biofortification in Soybean: Challenges and Prospects

Agronomy, 2023
Folate deficiency is a significant global health issue that affects millions of people and causes severe adverse effects. Major staple crops, which provide significant amounts of calories, often contain inadequate folate levels.
Kwadwo Gyapong Agyenim-Boateng, Shengrui Zhang, Md. Jahidul Islam Shohag, Abdulwahab S. Shaibu, Jing Li, Bin Li, Junming Sun   +6 more
doaj   +1 more source

Serum Folate in Asthma: Does it Correlate to Severity? A Single Center Experience [PDF]

Pediatric Sciences Journal, 2021
Background: Bronchial asthma is the most common chronic childhood illness. It is characterized by airway inflammation and episodic airflow obstruction.
Christine W.S. Basanti , Magd A. Kotb, Nagla F. Elsalawy, Nossaiba E. A. Telb, Azza K. Abdelmegeid   +4 more
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Clinical utility of serum folate measurement in tertiary care patients: Argument for revising reference range for serum folate from 3.0 ng/mL to 13.0 ng/mL

Practical Laboratory Medicine, 2015
Objective: Assess the need for folate testing, frequency of corrective action, and determine reference level for serum folate. Methods: Serum folate levels in 5313 samples from 4448 patients, and clinical data were reviewed for patient characteristics ...
Gurmukh Singh, Hana Hamdan, Vivek Singh
doaj   +1 more source