Results 51 to 60 of about 101,883 (259)

Sonoselective Transfection of Glioma Endothelium

Advanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski, Catherine M. Gorick, Victoria R. Breza, Jackson Tirrell, Krishan Perumal, Katherine M. Nowak, Ji Song, Natasha D. Sheybani, Richard J. Price   +8 more
wiley   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, EarlyView.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Pengaruh suplementasi besi-folat, vitamin A dan seng terhadap durasi dan frekuensi sakit ISPA pada anak sekolah dasar dengan status gizi kurang di Kabupaten Bantul

Jurnal Gizi Klinik Indonesia, 2007
Background: Children in school-age are categorized as sensitive group who are in the second fast growth so that adequate nutrition intake is needed. Under-nourished students tend to have low immune and susceptible to illness.
Sri Mulyati, Madarina Julia, Abidillah Mursyid   +2 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Late-life dietary folate restriction reduces biosynthesis without compromising healthspan in mice

Life Science Alliance
Low folate levels reduce anabolism, make yeast and worms live longer, and improve the metabolic flexibility of old mice. Folate is a vitamin required for cell growth and is present in fortified foods in the form of folic acid to prevent congenital ...
Heidi M Blank, Staci E Hammer, Laurel Boatright, Courtney Roberts, Katarina E Heyden, Aravindh Nagarajan, Mitsuhiro Tsuchiya, Marcel Brun, Charles D Johnson, Patrick J Stover, Raquel Sitcheran, Brian K Kennedy, L Garry Adams, Matt Kaeberlein, Martha S Field, David W Threadgill, Helene L Andrews-Polymenis, Michael Polymenis   +17 more
doaj   +1 more source

Effect of Different Cooking Methods on Folate Content in Chicken Liver

Foods, 2020
Common liver sources in European countries include cow, chicken, duck, lamb and pig. Despite its decreasing popularity, liver is possibly one of the most nutrient-dense foods, being rich in high-quality protein and low in calories.
Marta Czarnowska-Kujawska, Anna Draszanowska, Elżbieta Gujska   +2 more
doaj   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Folate in the United States Population and its Association with Congestive Heart Failure

Reviews in Cardiovascular Medicine
Background: To investigate the relationship between red blood cell (RBC) folate and congestive heart failure (CHF). Methods: We extracted the concentrations of RBC folate and collated CHF information from the National Health and Nutrition Examination ...
Longbo Wang, Fangcong Yu, Jiaran Shi, Tianxin Ye, Yunping Zhou, Zhuonan Sun, Jinxiu Yang, Xingxiang Wang   +7 more
doaj   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Associations of polycyclic aromatic hydrocarbons exposure with mortality and effect modification by folate biomarkers in a prospective population

Environmental Chemistry and Ecotoxicology
The associations of folate biomarkers and polycyclic aromatic hydrocarbons (PAHs) in the general population remain unclear. Therefore, this study aimed to examine whether folate biomarkers are associated with PAHs, and whether folate biomarkers can ...
Siyu Duan, Kairong Wang, Chenming Gu, Junmin Zhu, Yafei Wu, Ya Fang   +5 more
doaj   +1 more source