Results 71 to 80 of about 815,913 (302)

Estimated secondary structure propensities within V1/V2 region of HIV gp120 are an important global antibody neutralization sensitivity determinant.

PLoS ONE, 2014
BackgroundNeutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly between the isolates. Significant role of V1/V2 domain as a global neutralization sensitivity regulator has been suggested.
Maxim Totrov
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Ageing behaviour of folded joints produced by fusion bonding of an outer metal sheet and an inner organic sheet

Journal of Advanced Joining Processes
Adhesive hemming is a process used in the automotive industry to join two metal sheets with good structural performance and good optical appearance of the rim. A new approach is to replace the inner metal sheet by a fibre-reinforced thermoplastic polymer
Holger Deutges, Klaus Dilger, Sven Hartwig   +2 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

F-theory on 6D symmetric toroidal orbifolds

Journal of High Energy Physics, 2022
In this work we study F-theory on symmetric toroidal orbifolds that exhibit roto-translations, which are point group rotations accompanied by fractional lattice shifts. These geometries admit a rich class of effects, such as twisted affine folded fibers,
Finn Bjarne Kohl, Magdalena Larfors, Paul-Konstantin Oehlmann   +2 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

The Folded Paper Size Illusion: Evidence of Inability to Perceptually Integrate More Than One Geometrical Dimension

i-Perception, 2016
The folded paper-size illusion is as easy to demonstrate as it is powerful in generating insights into perceptual processing: First take two A4 sheets of paper, one original sized, another halved by folding, then compare them in terms of area size by ...
Claus-Christian Carbon
doaj   +1 more source

Computational analyses decipher the primordial folding coding the 3D structure of the beetle horn

Scientific Reports, 2021
The beetle horn primordium is a complex and compactly folded epithelial sheet located beneath the larval cuticle. Only by unfolding the primordium can the complete 3D shape of the horn appear, suggesting that the morphology of beetle horns is encoded in ...
Keisuke Matsuda, Hiroki Gotoh, Haruhiko Adachi, Yasuhiro Inoue, Shigeru Kondo   +4 more
doaj   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Modelling Impact Damage in Sandwich Structures with Folded Composite Cores [PDF]

, 2010
The paper describes FE simulation methods for novel folded structural composite cores being developed for sandwich structures with enhanced performance for use in aircraft fuselage and wing primary structures.
Johnson, Alastair, Kilchert, Sebastian
core