Results 51 to 60 of about 152,541 (294)
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
AIP Advances, 2020 In this paper, a novel angular log-periodic folded groove waveguide (ALFGW) slow-wave structure (SWS) has been investigated theoretically and experimentally for application in Ka-band traveling-wave tubes (TWTs).
Hexin Wang +11 more
doaj +1 more source
Systematic validation of protein force fields against experimental data. [PDF]
PLoS ONE, 2012 Molecular dynamics simulations provide a vehicle for capturing the structures, motions, and interactions of biological macromolecules in full atomic detail.
Kresten Lindorff-Larsen +5 more
doaj +1 more source
Planning to fold multiple objects from a single self-folding sheet [PDF]
Robotica, 2011 SUMMARYThis paper considers planning and control algorithms that enable a programmable sheet to realize different shapes by autonomous folding. Prior work on self-reconfiguring machines has considered modular systems in which independent units coordinate with their neighbors to realize a desired shape.
An, Byoung Kwon +3 more
openaire +3 more sources
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Advanced Intelligent Systems, 2022 The origami technique realizes unique mechanical properties of sheet materials without additional parts. Herein, a self‐folded corrugated structure (SCS) is developed based on the reinforcing properties of the origami technique. The corrugated structures
Yuki Fukatsu, Hiroki Shigemune
doaj +1 more source
Heliyon, 2022 This study aims to observe the possibility of using tire shreds as sustainable waste materials by including a geogrid wrap-around sheet to improve the response of load-settlement of the sandy bed.
Hussein Ahmad
doaj +1 more source
Designing protein β-sheet surfaces by Z-score optimization [PDF]
, 2000 Studies of lattice models of proteins have suggested that the appropriate energy expression for protein design may include nonthermodynamic terms to accommodate negative design concerns.
Datta, Deepshikha +3 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
Computational analyses decipher the primordial folding coding the 3D structure of the beetle horn
Scientific Reports, 2021 The beetle horn primordium is a complex and compactly folded epithelial sheet located beneath the larval cuticle. Only by unfolding the primordium can the complete 3D shape of the horn appear, suggesting that the morphology of beetle horns is encoded in ...
Keisuke Matsuda +4 more
doaj +1 more source