Results 51 to 60 of about 815,913 (302)

The bending of cell sheets - from folding to rolling [PDF]

open access: yesBMC Biology, 2011
The bending of cell sheets plays a major role in multicellular embryonic morphogenesis. Recent advances are leading to a deeper understanding of how the biophysical properties and the force-producing behaviors of cells are regulated, and how these forces are integrated across cell sheets during bending.
Keller Ray, Shook David
openaire   +3 more sources

Graphene as a Prototypical Model for Two-Dimensional Continuous Mechanics

open access: yesApplied Sciences, 2017
This paper reviews a few problems where continuous-medium theory specialized to two-dimensional media provides a qualitatively correct picture of the mechanical behavior of graphene. A critical analysis of the parameters involved is given.
Philippe Lambin
doaj   +1 more source

Systematic validation of protein force fields against experimental data. [PDF]

open access: yesPLoS ONE, 2012
Molecular dynamics simulations provide a vehicle for capturing the structures, motions, and interactions of biological macromolecules in full atomic detail.
Kresten Lindorff-Larsen   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Slot Array Antenna using Folded Waveguides [PDF]

open access: yes, 2005
A highly compact slot array antenna using substrate integrated folded waveguides (SIFW) is proposed in this paper. The device has three key components: a non adiating SMA to standard waveguide transition, a power divider from standard waveguide to folded
Sanz-Izquierdo, Benito   +4 more
core  

Monitoring the Disulfide Bonds of Folding Isomers of Synthetic CTX A3 Polypeptide Using MS-Based Technology

open access: yesToxins, 2019
Native disulfide formation is crucial to the process of disulfide-rich protein folding in vitro. As such, analysis of the disulfide bonds can be used to track the process of the folding reaction; however, the diverse structural isomers interfere with ...
Sheng-Yu Huang   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Adjustable thermal resistor by reversibly folding a graphene sheet [PDF]

open access: yesNanoscale, 2016
Phononic (thermal) devices are studied such as thermal diode, thermal transistors, thermal logic gates, and thermal memories. However, the thermal resistor has not been demonstrated yet. Here, we propose an instantaneously adjustable thermal resistor by folded graphene.
Song, Qichen   +5 more
openaire   +3 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Decoding Structural Properties of a Partially Unfolded Protein Substrate: En Route to Chaperone Binding. [PDF]

open access: yesPLoS Computational Biology, 2015
Many proteins comprising of complex topologies require molecular chaperones to achieve their unique three-dimensional folded structure. The E.coli chaperone, GroEL binds with a large number of unfolded and partially folded proteins, to facilitate proper ...
Suhani Nagpal   +3 more
doaj   +1 more source

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