Results 41 to 50 of about 10,115,388 (315)
Growth in a Turing Model of Cortical Folding
Biomath, 2012 The brain's cerebral cortex is folded into many gyri (hills) and sulci (valleys). Little is known about how the cortex folds or why the folds are located where they are.
Gregory Toole, Monica K. Hurdal
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Skin Barrier Formation: The Membrane Folding Model [PDF]
Journal of Investigative Dermatology, 2001 We propose that skin barrier morphogenesis may take place via a continuous and highly dynamic process of intersection-free membrane unfolding with a concomitant crystallization of the emerging multilamellar lipid structure representing the developing skin barrier.
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Folding model analysis of alpha radioactivity [PDF]
Journal of Physics G: Nuclear and Particle Physics, 2003 Radioactive decay of nuclei via emission of $α$ particles has been studied theoretically in the framework of a superasymmetric fission model using the double folding (DF) procedure for obtaining the $α$-nucleus interaction potential. The DF nuclear potential has been obtained by folding in the density distribution functions of the $α$ nucleus and the ...
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Ring-like N-fold Models of Aβ42 fibrils [PDF]
Scientific Reports, 2017 AbstractWhen assembling as fibrils Aβ40 peptides can only assume U-shaped conformations while Aβ42 can also arrange as S-shaped three-stranded chains. We show that this allows Aβ42 peptides to assemble pore-like structures that may explain their higher toxicity.
Wenhui Xi, Ulrich H. E. Hansmann
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Protein GB1 folding and assembly from structural elements. [PDF]
, 2009 Folding of the Protein G B1 domain (PGB1) shifts with increasing salt concentration from a cooperative assembly of inherently unstructured subdomains to an assembly of partly pre-folded structures.
Xue, Wei-Feng +6 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain [PDF]
, 2011 Riboswitch RNAs fold into complex tertiary structures upon binding to their cognate ligand. Ligand recognition is accomplished by key residues in the binding pocket.
Julia Wirmer-Bartoschek +17 more
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BioData Mining, 2019 Background Machine learning strategies are prominent tools for data analysis. Especially in life sciences, they have become increasingly important to handle the growing datasets collected by the scientific community.
Sebastian Bittrich +5 more
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Nasolabial folds modeling — literature review
Journal of Face Aesthetics, 2019 Introduction. Nasolabial folds are skin folds that run from both sides of the nose to the corners of the mouth. They are caused by the loss of fat in the dermis, followed by the loss of muscles in the middle part of the face.Aim. The aim of the work is to present contemporary knowledge of materials used for modeling nasolabial folds.Material and ...
Teresa Matthews‑Brzozowska +2 more
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