Results 51 to 60 of about 222,091 (247)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Engineered ScienceDuring the working process of the folding wing, there is not only a large-range rigid body motion but also a deformation motion of the flexible components. The problem of the rigid-flexible coupling of the structure is extremely complex.
Xinqiang Lu, Rui Yang, Shiyong Sun
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Folding models for elastic and inelastic scattering [PDF]
, 2005 The most widely used models are the optical model potential (OMP) for elastic scattering, and its generalization to non-spherical shapes, the deformed optical model potential (DOMP) for inelastic scattering. These models are simple and phenomenological; their parameters are adjusted so as to reproduce empirical data. Nonetheless, there are certain, not
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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AIP AdvancesFor meeting the requirements of tactical missiles seeking miniaturized launch devices for storage, transportation, and launch, a tube-launched missile wing is adopted, which folds before launch and quickly unfolds after launch.
Tiegang Lv +7 more
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Aerodynamic Analysis and Simulation for a Z-Shaped Folding Wing UAV
AerospaceThe potential of folding wing unmanned aerial vehicles (UAVs) in enhancing the adaptability of complex missions is substantial. Analyzing the aerodynamic characteristics of these UAVs is vital for optimizing the design of their folding wing configuration
Jin-Gang Wang, Xiang-Ying Guo
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Free energy landscape and multiple folding pathways of an H-type RNA pseudoknot. [PDF]
PLoS ONE, 2015 How RNA sequences fold to specific tertiary structures is one of the key problems for understanding their dynamics and functions. Here, we study the folding process of an H-type RNA pseudoknot by performing a large-scale all-atom MD simulation and bias ...
Yunqiang Bian +4 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Tissue-scale in vitro epithelial wrinkling and wrinkle-to-fold transition
Nature CommunicationsAlthough epithelial folding is commonly studied using in vivo animal models, such models exhibit critical limitations in terms of real-time observation and independent control of experimental parameters.
Jaeseung Youn +4 more
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Applied SciencesThe rapid deployment of folding wings is characterized by high-energy impacts, which require an immediate and effective response from the locking mechanism.
Guangqing Zhai +6 more
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