Results 51 to 60 of about 217,044 (288)

Material parameter computation for multi-layered vocal fold models [PDF]

open access: yesThe Journal of the Acoustical Society of America, 2011
Today, the prevention and treatment of voice disorders is an ever-increasing health concern. Since many occupations rely on verbal communication, vocal health is necessary just to maintain one’s livelihood. Commonly applied models to study vocal fold vibrations and air flow distributions are self sustained physical models of the larynx composed of ...
Bastian, Schmidt   +4 more
openaire   +2 more sources

Sensitivity of nucleon-nucleus scattering to the off-shell behavior of on-shell equivalent NN potentials [PDF]

open access: yes, 1996
The sensitivity of nucleon-nucleus elastic scattering to the off-shell behavior of realistic nucleon-nucleon interactions is investigated when on-shell equivalent nucleon-nucleon potentials are used. The study is based on applications of the full-folding
A. K. Kerman   +35 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Unfolding Crease Patterns Inspired by Insect Wings and Variations of the Miura-ori with a Single Vein

open access: yesBiomimetics, 2019
In many disciplines, professionals are interested in folding patterns for their packing and shape changing capabilities. Many insects have folded wings fitting to their body morphology that can unfold to fly, support their weight and withstand external ...
Thibaut Houette   +2 more
doaj   +1 more source

Resonance-Driven Passive Folding/Unfolding Flapping Wing Actuator

open access: yesApplied Sciences, 2020
The wings of flapping-wing micro aerial vehicles (MAVs) face the risk of breakage. To solve this issue, we propose the use of a biomimetic foldable wing.
Takashi Ozaki   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

BiP clustering facilitates protein folding in the endoplasmic reticulum. [PDF]

open access: yesPLoS Computational Biology, 2014
The chaperone BiP participates in several regulatory processes within the endoplasmic reticulum (ER): translocation, protein folding, and ER-associated degradation. To facilitate protein folding, a cooperative mechanism known as entropic pulling has been
Marc Griesemer   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Microscopic calculations of medium effects for 200-MeV (p,p') reactions [PDF]

open access: yes, 1999
We examine the quality of a G-matrix calculation of the effective nucleon-nucleon (NN) interaction for the prediction of the cross section and analyzing power for 200-MeV (p,p') reactions that populate natural parity states in $^{16}$O, $^{28}$Si, and $^{
A. De Pace   +74 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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