Results 61 to 70 of about 391,837 (318)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Single-molecule fluorescence studies of Protein Folding and Molecular Chaperones [PDF]
, 2011 Folding of newly synthesized proteins is an essential part of protein biosynthesis and misfolding can result in protein aggregation which can also lead to several severe diseases.
Sikor, Martin
core
Protein folding disorders: Toward a basic biological paradigm
, 2010 Mechanistic 'physics' models of protein folding fail to account for the observed spectrum of protein folding and aggregation disorders, suggesting that a more appropriately biological paradigm will be needed for understanding the etiology ...
Rodrick Wallace
core +1 more source
Single time-point analysis of product and substrate inhibition
Scientific ReportsWhen enzyme inhibition by either the product or excess substrate occurs, it is possible to determine the characteristic kinetic parameters based on [P]/t measurements, even when a large proportion of the substrate is converted.
Olivier Verlaine +4 more
doaj +1 more source
Trans-translation exposed: understanding the structures and functions of tmRNA-SmpB
Frontiers in Microbiology, 2014 Ribosome stalling is a serious issue for cell survival. In bacteria, the primary rescue system is trans-translation, performed by tmRNA and its protein partner small protein B (SmpB).
Emmanuel eGIUDICE +2 more
doaj +1 more source
Remote Sensing, 2021 Clouds constitute a major obstacle to the application of optical remote-sensing images as they destroy the continuity of the ground information in the images and reduce their utilization rate.
Xiaolong Li +6 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2010 Protein folding disorders of aging like Alzheimer's and Parkinson's diseases currently present intractable medical challenges. 'Small molecule' interventions - drug treatments - often have, at best, palliative impact, failing to alter
Rodrick Wallace
core +1 more source
Minimal Retraction of Space-time and Their Foldings [PDF]
, 2009 The folding of a manifold was, firstly introduced by Robertson in [1977] . Since then many authers have studied the folding of manifolds s. The deformation retracts of the manifolds defined and discussed.
El-Ahmady, A. E., Rafat, H.
core +1 more source
, 2022 Video of the Pyramidal origami structure self-folding into its initial stable state and subsequently reconfigured to its second stable ...
Salvador Rojas (13861903) +2 more
core +1 more source