Results 121 to 130 of about 5,115,772 (341)

Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pemetrexed is a cornerstone in chemo(immunotherapy) of non‐small cell lung cancer and mesothelioma; however, it is contraindicated in patients with renal impairment due to severe toxicity concerns. Therefore, a large proportion of patients is withheld from effective chemo(immunotherapy).
Nikki de Rouw   +18 more
wiley   +1 more source

The primary prevention of birth defects: Multivitamins or folic acid?

open access: yesInternational Journal of Medical Sciences, 2004
Periconceptional use of folic acid alone or in multivitamin supplements is effective for the primary prevention of neural-tube defects. The Hungarian randomized and two-cohort controlled trials showed that periconceptional multivitamin supplementation ...
doaj  

Observations on the effects of the folic acid antagonists, aminopterin and amethopterin, in patients with advanced neoplasms [PDF]

open access: bronze, 1952
Emanuel B. Schoenbach   +2 more
openalex   +1 more source

Recent Advances and Constructing Strategies of Chemiluminescence‐ and Bioluminescence‐Based Photodynamic Therapy

open access: yesChemPhotoChem, EarlyView.
Photodynamic therapy (PDT) is a noninvasive therapy for cancer and many other diseases. A PDT system includes three key components: a light source, photosensitizers (PSs), and oxygen. Internal light sources, such as chemiluminescence (CL) and bioluminescence (BL), trigger PDT without external irradiation, allowing for more flexibility.
Yuqin Ge, Shuyan Xue, Zhonghua Chen
wiley   +1 more source

Quantitative Investigation of Nitrosamine Drug Substance‐Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis

open access: yesDrug Testing and Analysis, EarlyView.
The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel   +5 more
wiley   +1 more source

Magnetic Layered Double Hydroxide Nanocomposites: Synthesis, Catalytic Performances, Environmental and Biological Applications

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review involves a comprehensive study on the diverse applications of the magnetic layered double hydroxides (LDHs) including their catalytic performances, as well as, environmental and biological functions. Moreover, different strategies utilized for the synthesis of LDH‐based composites are described.
Mohammad Mavvaji   +2 more
wiley   +1 more source

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

open access: yesEye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang   +9 more
wiley   +1 more source

On the Occurrence of Folic Acid, Folic Acid Conjugates, and Folic Acid Conjugases in Pollen. [PDF]

open access: yesActa Chemica Scandinavica, 1957
Niels Nielsen   +4 more
openaire   +2 more sources

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