Results 131 to 140 of about 8,616,641 (354)

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (FACT): double blind, phase III, randomised controlled, international, multicentre trial

open access: yesBritish medical journal, 2018
Objective To determine the efficacy of high dose folic acid supplementation for prevention of pre-eclampsia in women with at least one risk factor: pre-existing hypertension, prepregnancy diabetes (type 1 or 2), twin pregnancy, pre-eclampsia in a ...
Wu-Wen Shi   +21 more
semanticscholar   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Effect of dietary folic acid supplementation on folic acid content, egg quality and egg yield of captive Huabei Chai chickens

open access: yesSiliao yanjiu, 2022
The experiment was to study the effect of dietary folic acid on content of folic acid in egg yolk, egg quality and egg yield of Huabei Chai chickens.
Shuai-qiang MAO   +7 more
doaj  

Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy

open access: yesNanomaterials and Nanotechnology, 2015
This paper presents a study of adsorption and vibrational features of folic acid, using surface-enhanced Raman scattering (SERS). A gold-capped silicon nanopillar (Au NP) with a height of 600 nm and a width of 120 nm was utilized to study the vibrational
John J. Castillo   +3 more
doaj   +1 more source

In Vivo Studies of Magnetic Nanoparticles-Folic Acid (FA) Functionalized for Breast Cancer Targeting Drug Carrier [PDF]

open access: yes, 2023
. The number of cancer patients in the world is constantly increasing and it is considered as one of the deadliest among other diseases. There are urgent needs of effective and efficient medicine for late-stage cancer since none of current treatment has ...
Erdinandus Hartono, -   +2 more
core  

Synthesis of Oligonucleotide Conjugates Employing a Diselenide Linker

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT In this study, we report the synthesis of an alkylene linker containing a terminal 2‐cyanoethyl protected selenium functionality for coupling at the 5'‐end of an oligonucleotide by solid phase synthesis for the preparation of oligonucleotide conjugates.
Shivam Tikoo   +2 more
wiley   +1 more source

Nutrition awareness of folic acid among Thai women

open access: yes, 2003
The objective of this study was to determine Thai women's nutrition awareness of folic acid and its role in the prevention of neural tube defects. Three hundred and two Thai women between 18-45 years completed a 30 itemized survey.
Strahley, Monica L.
core  

A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells

open access: yesChemistry – A European Journal, EarlyView.
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak   +9 more
wiley   +1 more source

A British Pharmacological Society Position Statement on Medications in Pregnancy and Lactation

open access: yes
British Journal of Clinical Pharmacology, EarlyView.
Agnesa Mustafa   +14 more
wiley   +1 more source

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