Folic acid: a potential inhibitor against SARS-CoV-2 nucleocapsid protein
Context Coronavirus disease 2019 is a global pandemic. Studies suggest that folic acid has antiviral effects. Molecular docking shown that folic acid can act on SARS-CoV-2 Nucleocapsid Phosphoprotein (SARS-CoV-2 N).Objective To identify novel molecular ...
Yu-meng Chen+6 more
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Folic acid metabolism in Rauscher murine leukemia and effect of methotrexate on the blood picture [PDF]
Folic acid contents of plasma, whole blood, liver and spleen in Rauscher leukemic mice were estimated. Plasma and liver folate in the leukemic mice was lower than that of normal mice, suggesting that folic acid was deficient in Rauscher leukemia.
Sanada, Hiroshi, Taguchi, Hirokuni
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After peripheral nerve injury, intraperitoneal injection of folic acid improves axon quantity, increases axon density and improves electromyography results. However, the mechanisms for this remain unclear.
Wei-Bo Kang+3 more
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Clinical and experimental studies on folic acid deficiency due to anticonvulsants. 2. Investigations on patients receiving anticonvulsants and experimental study on the effect of diphenylhydantoin on the absorption of folic acid in rats [PDF]
A high incidence of subnormal serum folic acid levels was observed in 48 patients receiving anticonvulsants (75 %). In peripheral blood, macrocytosis was detected in 46 % and an increase of hypersegmented neutrophils was also seen in 24 % of the patients.
Taguchi, Hirokuni
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Background Folic acid fortification of staple foods has been in place in many countries for over two decades. Studies have shown that folic acid fortification can significantly reduce incidence of neural tube defects.
Ipyana Frank Mwandelile+5 more
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Photochemical Synthesis of the Bioconjugate Folic Acid-Gold Nanoparticles [PDF]
In this paper we present a rapid and simple onepot method to obtain gold nanoparticles functionalized with folic acid using a photochemistry method. The bioconjugate folic acid-gold nanoparticle was generated in one step using a photo-reduction method ...
Bertel, Linda+3 more
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Folic acid awareness and usage among females at Saudi Electronic University in Jeddah, Saudi Arabia
Objectives: This study evaluates awareness of folic acid and neural tube defects, use of folic acid and knowledge of folic acid usage among female university students in Saudi Arabia.
Mohammed AL-Mohaithef+3 more
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Protein particles have been reported as the potential carriers for the co-encapsulation of bioactive components. In this study, lysozyme, a basic protein, was used to simultaneously encapsulate folic acid and α-tocopherol at pH 4.0.
Lingling Ma+5 more
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Folic Acid Antagonists: Antimicrobial and Immunomodulating Mechanisms and Applications
Bacterial, protozoan and other microbial infections share an accelerated metabolic rate. In order to ensure a proper functioning of cell replication and proteins and nucleic acids synthesis processes, folate metabolism rate is also increased in these ...
D. Fernández-Villa, M. Aguilar, L. Rojo
semanticscholar +1 more source
Effect of folic acid and metformin on insulin resistance and inflammatory factors of obese children and adolescents [PDF]
Background: Considering the increasing trend of obesity, especially in developing countries such as Iran, and the role of inflammatory factors and insulin resistance (IR) in the occurrence of obesity-related complications as well as the safety of some ...
Atabek+35 more
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