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The association between medication use and vitamin B<sub>12</sub> deficiency in the elderly population: a cross- sectional study. [PDF]
BMC GeriatrTillemans MPH +3 more
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Treatment of Psoriasis with Folic Acid Antagonists
Archives of Dermatology, 1958Since the reporting of clinical improvement observed in the treatment of psoriasis with aminopterin, 1 our interest has been aroused to reevaluate the results obtained with this drug as well as with its close relative amethopterin. These drugs were used in our private practice in relatively low but therapeutic dosage.
W F, EDMUNDSON, W B, GUY
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Risk of Fetal Exposure to Folic Acid Antagonists
Journal of Obstetrics and Gynaecology Canada, 2004Several folic acid antagonists are considered by the Food and Drug Administration (FDA) to be toxic or potentially toxic to fetuses, including some folic acid antagonists that were once considered safe, such as trimethoprim. Information on fetal exposure to folic acid antagonists is sparse.In this study, we conducted a thorough search of English ...
Shi Wu Wen, Mark Walker
exaly +3 more sources
Reproductive Toxicology, 2005
Since the protective effect of folic acid (FA) on birth defects is well known, it is reasonable to assume intrauterine exposure to FA antagonists increases the risk on these defects. We have therefore performed case-control analyses to investigate the risk of intrauterine exposure to FA antagonists, using data on births from the EUROCAT Northern ...
Willemijn M Meijer +2 more
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Since the protective effect of folic acid (FA) on birth defects is well known, it is reasonable to assume intrauterine exposure to FA antagonists increases the risk on these defects. We have therefore performed case-control analyses to investigate the risk of intrauterine exposure to FA antagonists, using data on births from the EUROCAT Northern ...
Willemijn M Meijer +2 more
exaly +3 more sources
Sulfonamides and Folic Acid Antagonists: A Historical Review
Journal of Nutrition, 1987E L Stokstad +2 more
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Immunopharmacology and Immunotoxicology, 1992
The influence of folic acid and several antagonists of the folic acid metabolism on neutrophil superoxide generation was investigated with the cytochrome c reduction assay. The compounds were found to be partial competitive inhibitors of the NADPH oxidase, their activity apparently increasing with larger substituents at the 10 position.
G F, Weber, M G, Nair
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The influence of folic acid and several antagonists of the folic acid metabolism on neutrophil superoxide generation was investigated with the cytochrome c reduction assay. The compounds were found to be partial competitive inhibitors of the NADPH oxidase, their activity apparently increasing with larger substituents at the 10 position.
G F, Weber, M G, Nair
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Folic Acid, its Analogs and Antagonists
1960Publisher Summary Folic acid has many functions in the body, and when it is lacking, anemia is only part of a generalized disorder that undermines the health of the sufferer. After a brief historical review, this chapter deals with the metabolic functions of folic acid. The actions of folic acid antagonists are considered and attention is directed to
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Scurvy Following Folic Acid Antagonist Therapy
Radiology, 1956Although folic acid antagonists have been widely used in recent years, there have been only a few reports of their effects on Vitamin C metabolism. Recently, we have seen a patient with widespread neuroblastoma in whom typical scorbutic changes developed in the long bones during the course of aminopterin therapy. Case Report B. P., a 16-month-old white
J M, DENNIS, R, MERCADO
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