Results 71 to 80 of about 5,946 (203)
MAFF Suppresses Necroptosis in Pancreatic Cancer via the GATA4‐MLKL Axis
Cancer Science, EarlyView.MAFF promotes pancreatic cancer progression by acting as a transcriptional repressor of the GATA4‐MLKL axis, thereby inhibiting necroptotic cell death. This study identifies the MAFF‐GATA4‐MLKL pathway as a novel therapeutic target and a significant prognostic biomarker for pancreatic adenocarcinoma.
Xinwei Zhou +3 more
wiley +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective To evaluate the effect of inositol supplementation on biochemical hyperandrogenism in women with polycystic ovary syndrome (PCOS) and to explore whether metabolic phenotype modifies the endocrine response. Design Systematic review and meta‐analysis of randomized controlled trials conducted in accordance with PRISMA guidelines ...
Daniele Tienforti +10 more
wiley +1 more source
The FEBS Journal, EarlyView.Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet +6 more
wiley +1 more source
Dialysis and Pregnancy: Optimizing Therapy for Best Maternal and Fetal Outcomes
Hemodialysis International, EarlyView.ABSTRACT Pregnancy in women with end‐stage kidney disease (ESKD) requiring dialysis remains high risk, with significant maternal and fetal complications. While fertility rates are markedly reduced in this population, advances in dialysis care and obstetric management have led to increasing reports of successful pregnancies.
Shreepriya Mangalgi, Silvi Shah
wiley +1 more source
Synergistic antimicrobial activities of folic acid antagonists and nucleoside analogs. [PDF]
Antimicrob Agents Chemother, 2010 Zander J +3 more
europepmc +1 more source
International Journal of Cosmetic Science, EarlyView.Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh +5 more
wiley +1 more source
Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta‐Analysis
Journal of Clinical Periodontology, EarlyView.ABSTRACT Objective To identify risk factors/indicators of gingival enlargement (GE) and to summarise evidence for its management. Methods A systematic review was undertaken following PRISMA guidelines and divided into PECOTS and PICOTS questions, related to risk factors/indicators and treatment studies, respectively.
Luigi Nibali +5 more
wiley +1 more source
De novo stolon organogenesis in potato leaf callus elicited by Agrobacterium tumefaciens stimulus
Journal of Integrative Plant Biology, EarlyView.Agrobacterium tumefaciens triggers stolon regeneration from potato leaf callus independent of T‐DNA insertion, suggesting a strategy to reprogram callus identity and expand the potential of tissue regeneration. ABSTRACT Plant cells can undergo cellular reprogramming, enabling pluripotent callus formation from excised leaves.
Seung Yong Shin +7 more
wiley +1 more source
Journal of Integrative Plant Biology, EarlyView.This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon +2 more
wiley +1 more source