The Concept of Folic Acid in Health and Disease
Folates have a pterine core structure and high metabolic activity due to their ability to accept electrons and react with O-, S-, N-, C-bounds.
Yulia Shulpekova+9 more
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A Mixed-Method Study to Determine the Benefits of Periconceptional Folic Acid Supplementation and Effects of Folic Acid Deficiency in Mothers on Birth Outcomes. [PDF]
BACKGROUND: Evidence from high income countries shows mothers who are supplemented with folic acid in their periconceptional period and early pregnancy have significantly reduced adverse outcomes like birth defects.
Allagh, Komal Preet+16 more
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Oral Manifestations of Nutritional Deficiencies: Single Centre Analysis
Introduction: Oral manifestations of deficiency of iron, vitamin B12 and folic acid are thought to be common. Prevalence of these deficiencies among patients with compatible symptoms is not well known.
Vladimíra Radochová+2 more
doaj +1 more source
Does Folic Acid Protect Patients with Inflammatory Bowel Disease from Complications?
Folic acid, referred to as vitamin B9, is a water-soluble substance, which participates in the synthesis of nucleic acids, amino acids, and proteins. Similarly to B12 and B6, vitamin B9 is involved in the metabolism of homocysteine, which is associated ...
A. Ratajczak+5 more
semanticscholar +1 more source
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. I. Clinical and nutritional study on megalobastic anemia due to anticonvulsants [PDF]
Two cases of megaloblastic anemia associated with anticonvulsant drugs were studied. Both cases were inpatients of psychiatric hospitals and had quite inadequate intakes of food. The former had lung tuber. culosis and the second had febril illness before
Taguchi, Hirokuni
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Association Between Folic Acid and Zinc Concentration with Incidence of Bacterial Vaginosis in the First Trimester of Pregnancy [PDF]
Bacterial vaginosis (BV) in pregnancy is associated with the increase of adverse pregnancy outcomes such as premature rupture of membranes and preterm labor. One of the multifactorial causes of BV is thechange in vaginal immunity. Malnutrition, including
Azmi, M. (Mohammad)+3 more
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Assessment of folic acid and DNA damage in cleft lip and cleft palate
Studies have identified the risk factors like folic acid deficiency during gestational period, family history for orofacial clefts, drugs like antiepileptic, vitamin A.
Sivakumar Brooklyin+4 more
doaj +1 more source
In 1998 a Tolerable Upper Intake Level (UL) for folic acid was established based on case reports from the 1940s suggesting that high-dosage folic acid intake, used to treat patients with pernicious anemia, had the potential to precipitate or speed-up the
R. Berry
semanticscholar +1 more source
Megaloblastic anemia in Japan [PDF]
Since 1903, 744 cases of megaloblastic anemia have been reported in Japan: 490 cases of pernicious anemia; 95 cases associated with pregnancy; 66 cases after gastrectomy; 22 cases of megaloblastic anemia of infants; 21 cases of folic acid deficiency ...
Taguchi, Hirokuni
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Preconception folic acid supplement use is a well-known method of primary prevention of neural tube defects (NTDs). Obese women are at a higher risk for having a child with a NTD.
M. van der Windt+5 more
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