Results 1 to 10 of about 212 (95)

Diarrhea with deficiency kidney-yang syndrome caused by adenine combined with Folium senna was associated with gut mucosal microbiota [PDF]

Frontiers in Microbiology, 2022
The present study aims to study and analyze the characteristics of gut mucosal microbiota in diarrhea mice with deficiency kidney-yang syndrome. Ten male mice were randomly divided into the control group and the model group.
Xiaoya Li, Zhoujin Tan, Xinxin Peng
exaly   +6 more sources

Folium Sennae Increased the Bioavailability of Methotrexate through Modulation on MRP 2 and BCRP [PDF]

Pharmaceuticals, 2021
Folium Sennae (FS), a popular laxative (Senna), contains polyphenolic anthranoids, whose conjugation metabolites are probable modulators of multidrug resistance-associated proteins (MRPs) and breast cancer resistance protein (BCRP). We suspected that the
Chung-Ping Yu, Yu-Hsuan Peng, Ching-Ya Huang, Yow-Wen Hsieh, Yu-Chi Hou, Shiuan-Pey Lin   +5 more
doaj   +5 more sources

Effective degradation of anthraquinones in Folium Sennae with Monascus fermentation for toxicity reduce and efficacy enhancement. [PDF]

Heliyon, 2023
Folium Sennae are widely used around the world, mainly in purging and removal of endogenous active substances, such as anthraquinone and its derivatives. However, the potential toxicity of anthraquinones to the liver, kidney, and intestinal limits the application of Folium Sennae.
Long M, Pei X, Lu Z, Xu D, Zheng N, Li Y, Ge H, Cao W, Osire T, Xia X.   +9 more
europepmc   +4 more sources

Intestinal microbiota characteristics of mice treated with Folium senna decoction gavage combined with restraint and tail pinch stress. [PDF]

3 Biotech, 2020
To investigate the characteristics of the intestinal microbiota of mice treated with Folium senna decoction gavage combined with restraint and tail pinch stress. Ten healthy male Kunming mice were chosen and randomly divided into control group and model group, with five mice in each group.
Yuan Z, Zhang C, Peng X, Shu L, Long C, Tan Z.   +5 more
europepmc   +4 more sources

Association of intestinal mucosal barrier function with intestinal microbiota in Spleen-Kidney Yang Deficiency IBS-D mice [PDF]

Frontiers in Microbiology
BackgroundTo establish and evaluate an IBS-D mouse model with Spleen-Kidney Yang Deficiency, explore the microecological mechanisms of IBS-D, and provide experimental evidence for the clinical diagnosis and treatment of IBS-D with Spleen-Kidney Yang ...
Liwen Li, Liwen Li, Qi Long, Qi Long, Na Deng, Na Deng, Zhoujin Tan, Zhoujin Tan   +7 more
doaj   +2 more sources

One mechanism of spleen-kidney yang deficiency IBS-D: intestinal microbiota affect ATPase [PDF]

Frontiers in Microbiology
BackgroundThis study aimed to investigate the effects of adenine and Folium senna combined with restraint tail-clamping stress method on the intestinal microbiota of mice with spleen-kidney yang deficiency type diarrhea predominant irritable bowel ...
Qi Long, Qi Long, Liwen Li, Liwen Li, Na Deng, Na Deng, Zhoujin Tan, Zhoujin Tan   +7 more
doaj   +2 more sources

Wei Chang An pill regulates gastrointestinal motility in a bidirectional manner [PDF]

Pharmaceutical Biology, 2021
Context Wei Chang An (WCA) is a commercial prescription developed for the coordination of gastrointestinal movement. Objective To investigate the role of WCA in the regulation of diarrhoea and constipation in rats.
Sitong Jia, Lijuan Chai, Jing Zhang, Min Zhang, Lin Li, Yaxin Qi, Yafen Pang, Xi Chen, Nana Fan, Lin Wang, Yujing Wang, Jixiang Song, Yingjie Sun, Yi Wang, Lin Miao, Han Zhang   +15 more
doaj   +2 more sources

Co-fermentation of Rosa roxburghii Tratt pulp by Saccharomyces cerevisiae and Bacillus subtilis alleviates diarrhea-predominant irritable bowel syndrome in mice by reshaping gut microbiota and host metabolism [PDF]

Frontiers in Nutrition
BackgroundDiarrhea-predominant irritable bowel syndrome (IBS-D) is a common functional bowel disorder closely associated with gut microbiota dysbiosis and gut-brain axis dysfunction. However, effective treatment options remain limited.
Jian Zhang, Jian Zhang, Shuo Zhang, Shuo Zhang, Shuo Zhang, Zhiyu Chen, Zhiyu Chen, Chencen Lai, Chencen Lai, Shiyu Zhang, Shiyu Zhang, Fangling Feng, Fangling Feng, Pengjiao Wang, Pengjiao Wang, Xuncai Huang, Min Zhang, Min Zhang, Xiuli Gao, Xiuli Gao, Xiuli Gao   +20 more
doaj   +2 more sources

Chinese herbal medicine, Tongxieyaofang, alleviates diarrhea via gut microbiota remodeling: evidence from network pharmacology and full-length 16S rRNA gene sequencing [PDF]

Frontiers in Cellular and Infection Microbiology
BackgroundTongxieyaofang (TXYF) was a traditional Chinese medicine (TCM) formula for the treatment of diarrhea with liver stagnation and spleen deficiency syndrome, but the potential targets and mechanisms have not been fully clarified.
Haoqing Shao, Liping Wang, Hualing Zhang
doaj   +2 more sources

Microbiome and metabolomic changes in rabbits induced by Folium sennae. [PDF]

PLoS One
Diarrhea is a serious health concern in livestock, affecting productivity and animal welfare. However, it remains a significant threat. Various practical therapies are being explored, such as prebiotics, probiotics, and organic acids, as well as chemical treatments including antibiotics, to combat this disorder.
Ding H, Li M, Ma N, Rajput SA, Almutairi MH, Almutairi BO, Han Z, Ma A, Shiau D.   +8 more
europepmc   +5 more sources