Results 21 to 30 of about 131,230 (368)

The first case of novel variants of the mutation causing primary amenorrhea in 2 siblings in Korea [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2022
Follicle-stimulating hormone receptor (FSHR) mutation is a rare cause of amenorrhea. We report the first case of FSHR mutations in Korea. Two female siblings, aged 16 (patient 1) and 19 (patient 2) years, were referred to the pediatric endocrinology ...
Sukdong Yoo, Ju Young Yoon, Changwon Keum, Chong Kun Cheon   +3 more
doaj   +1 more source

Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis

Reproductive Biology and Endocrinology, 2022
Follicle-stimulating hormone signaling is essential for the initiation and early stages of spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli cells.
Jia-Ming Wang, Zhen-Fang Li, Wan-Xi Yang, Fu-Qing Tan   +3 more
doaj   +1 more source

Follicle-Stimulating Hormone Receptor and Estrogen Receptor Gene Polymorphisms in Women With Discordant Follicle-Stimulating Hormone and Anti-Mullerian Hormone Levels. [PDF]

Cureus
Objective This study aimed to investigate follicle-stimulating hormone receptor (FSHR) polymorphisms (Thr307Ala and Asn680Ser), estrogen receptor 1 (ESR1) polymorphisms (PvuII and XbaI), and ESR2 polymorphisms (RsaI and AluI) in Turkish women with follicle-stimulating hormone (FSH) and anti-Mullerian hormone (AMH) discordance.
Aktaş G, Bertizlioglu M, Yılmaz SA, Kebapcılar AG, Çelik Ç, Seçilmiş Ö.   +5 more
europepmc   +3 more sources

Follicle-stimulating Hormone Interacts with Exoloop 3 of the Receptor [PDF]

Journal of Biological Chemistry, 2002
The human follicle-stimulating hormone (FSH) receptor consists of two distinct domains of approximately 330 amino acids, the N-terminal extracellular exodomain and membrane-associated endodomain including three exoloops and seven transmembrane helices.
Johann Sohn, Ki-Sung Ryu, Gail Sievert, Myoungkun Jeoung, Inhae Ji, Tae H. Ji   +5 more
openalex   +5 more sources

The enigma of the gonadotropin-releasing hormone pulse frequency governing individual secretion of luteinizing hormone and follicle-stimulating hormone

F&S Reports, 2023
Luteinizing hormone and follicle-stimulating hormone are the two gonadotropic pituitary hormones stimulated by one hypothalamic gonadotropin-releasing hormone (GnRH) in a pulsatile way.
Cornelis B. Lambalk, M.D., Ph.D.
doaj   +1 more source

Follicle-Stimulating Hormone Receptor

Definitions, 2020
Follicle-stimulating hormone receptor (695 aa, ~78 kDa) is encoded by the human FSHR gene. This protein is involved in the modulation of hormone binding and signaling and the mediation of both gonad development and gamete differentiation.

semanticscholar   +1 more source

Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors

Diseases, 2020
Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings.
Duaa Althumairy, Xiaoping Zhang, Nicholas Baez, George Barisas, Deborah A. Roess, George R. Bousfield, Debbie C. Crans   +6 more
doaj   +1 more source

Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]

, 2010
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H., De Gendt, K., Monteiro, A., O'Shaughnessy, P.J., Verhoeven, G.   +4 more
core   +2 more sources

Detection of FSH receptors in mouse and human penile tissue [PDF]

Journal of Men's Health
Background: This study aims to investigate the expression of follicle-stimulating hormone (FSH) receptors in both mouse and human penis to explore its potential impact on penis function.
Helen Zirnask, Pasi Pöllänen, Siim Suutre, Taavi Torga, Samuel Rüsse, Liis Salumäe, Andres Kotsar, Kersti Kokk   +7 more
doaj   +1 more source

Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]

, 2009
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H., Baker, P.J., Huhtaniemi, I., Morris, I.D., O'Shaughnessy, P.J.   +4 more
core   +1 more source