Results 231 to 240 of about 266,076 (313)

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong   +7 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Unexpected Cervical Lymph Node Metastasis Revealing TFE3‐Rearranged Renal Cell Carcinoma: Intraoperative Cytologic Clues to an Occult Renal Primary

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is a rare subtype of renal carcinoma that may present diagnostic challenges in cytologic specimens, particularly when metastatic disease represents the initial clinical manifestation. We report the case of a 72‐year‐old man presenting with bulky cervical lymphadenopathy clinically suspicious for
Marc P. Pusztaszeri
wiley   +1 more source

Cumulative Cytological Assessment of Repeated Non‐Diagnostic Thyroid Fine Needle Aspirations: A Novel Approach to Reduce Diagnostic Uncertainty

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Purpose Fine needle aspiration (FNA) is the primary diagnostic tool for evaluating thyroid nodules. However, 10%–21% of FNAs yield non‐diagnostic (ND) results (Bethesda category I). Repeated ND findings occur in 25%–67.5% of cases, creating diagnostic uncertainty and increased healthcare costs.
Shiri Damti Geva   +7 more
wiley   +1 more source

Irradiation with a mixed heavy ion beam induces ovarian follicle loss and dose-dependent mixed ovarian tumor development. [PDF]

open access: yesBiol Reprod
Leon Parada KN   +7 more
europepmc   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

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