Results 251 to 260 of about 287,286 (341)

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

Subcutaneous injection of genetically engineered exosomes for androgenic alopecia treatment. [PDF]

open access: yesFront Bioeng Biotechnol
Liu Y   +10 more
europepmc   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

open access: yesCancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai   +6 more
wiley   +1 more source

Transcriptome profiles of blastocysts originating from oocytes matured in follicular fluid from preovulatory follicles of greater or lesser maturity. [PDF]

open access: yesBMC Genomics
Stokes AE   +8 more
europepmc   +1 more source

Effect of Cytochrome P450 3A Inhibition and Induction by Itraconazole and Rifampin on Tazemetostat Pharmacokinetics in Patients With Advanced Malignancies

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This study (NCT04537715) investigated itraconazole (strong cytochrome P450 [CYP] 3A inhibitor) and rifampin (strong CYP3A inducer) on tazemetostat pharmacokinetics. In Part 1, patients received tazemetostat 400 mg orally on Days 1, 15, and 36, and 400 mg twice daily on Days 3‐14 and Days 21‐35.
Yingxue Chen   +6 more
wiley   +1 more source

Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
C. Higgins   +4 more
semanticscholar   +1 more source

OMIP‐114: A 36‐Color Spectral Flow Cytometry Panel for Detailed Analysis of T Cell Activation and Regulation in Small Human Blood Volumes

open access: yesCytometry Part A, EarlyView.
ABSTRACT This 36‐color flow cytometry panel is designed to characterize multiple lymphocyte compartments, with a focus on T cells, their memory subpopulations, and immune checkpoints in human whole blood samples. In clinical settings, the amount of blood available from patients for scientific research is often limited.
Marie‐Theres Thieme‐Ehlert   +3 more
wiley   +1 more source

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