Results 81 to 90 of about 2,475,670 (267)

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

open access: yesAdvanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang   +19 more
wiley   +1 more source

Isolation, Cultivation AND Differentiation of bulge hair follicle stem cells [PDF]

open access: yes
Background & Aims: Throughout life, stem cells make new cells in various tissues. Bulge region of hair follicle indicated as sources of stem cells for along times but little studies done in vitro to characterize rat bulge hair follicle stem cells ...
آسالگو, سارا   +2 more
core  

Activin B is produced early in antral follicular development and suppresses thecal androgen production [PDF]

open access: yes, 2012
Little is known about the role of activin B during folliculogenesis. This study investigated the expression levels of activin/inhibin subunits (βA, βB, and α), steroid enzyme, and gonadotrophin receptors in theca (TC) and granulosa cells (GC) by QPCR and
Young, J M   +5 more
core   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Electronics‐Free Visual Monitoring of Dry Eye Disease‐Related Tear Biomarkers Using Smart Scleral Lenses

open access: yesAdvanced Science, EarlyView.
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang   +15 more
wiley   +1 more source

Follicle stimulating hormone stimulates farnesyl-diphosphate farnesyltransferase 1 expression through LSD1Ser54p in chicken ovarian granulosa cells

open access: yesPoultry Science
Ovarian follicular development in laying hens is tightly regulated by a variety of endocrine and cellular factors, among which follicle-stimulating hormone (FSH) plays a decisive role.
Yanhong Zhang   +3 more
doaj   +1 more source

Hallmarks of Human Small Antral Follicle Development: Implications for Regulation of Ovarian Steroidogenesis and Selection of the Dominant Follicle

open access: yesFrontiers in Endocrinology, 2018
Regulation of human ovarian steroidogenesis differs from other species and precise knowledge on how human small antral follicles (hSAF) develop and acquire competence for continued growth and steroid output is still incomplete.
Stine G. Kristensen   +8 more
doaj   +1 more source

Evidence that fibroblast growth factor 10 plays a role in follicle selection in cattle

open access: yes, 2017
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)ACSCProcesso FAPESP: 2008/57365-2There is evidence that regulation of follicle selection in cattle involves locally produced growth factors. In the present study, we investigated the expression
Gasperin, B. G.   +14 more
core   +1 more source

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen   +13 more
wiley   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

open access: yesAdvanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen   +7 more
wiley   +1 more source

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