Follicle-Stimulating Hormone Glycobiology [PDF]
FSH glycosylation varies in two functionally important aspects: microheterogeneity, resulting from oligosaccharide structure variation, and macroheterogeneity, arising from partial FSHβ subunit glycosylation. Although advances in mass spectrometry permit extensive characterization of FSH glycan populations, microheterogeneity remains difficult to ...
George R Bousfield, David J Harvey
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Role of Follicle-Stimulating Hormone in Spermatogenesis [PDF]
Spermatogenesis is a concerted sequence of events during maturation of spermatogonia into spermatozoa. The process involves differential gene-expression and cell-cell interplay regulated by the key endocrine stimuli, i.e., follicle-stimulating hormone (FSH) and luteinizing hormone (LH)-stimulated testosterone.
Hellevi Peltoketo+3 more
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Follicle-Stimulating Hormone Receptors in Oocytes? [PDF]
The regulatory mechanisms of oocyte maturation remain poorly understood. Although gonadotropins play a major role in these processes, they have generally been considered to act on somatic supportive cells, but not directly on germ cells. We have raised high affinity monoclonal antibodies against LH and FSH receptors.
Meduri, G.+7 more
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Recombinant follicle stimulating hormone is effective in poor responders to highly purified follicle stimulating hormone [PDF]
Ovarian stimulation in cases of poor ovarian responsiveness is an important challenge in in-vitro fertilization (IVF) programmes. Despite improvements in oocyte number and quality, an ideal ovarian stimulation strategy has yet to be defined. Here, the results of ovarian stimulation with recombinant follicle stimulating hormone (rFSH) in 28 poor ...
DE PLACIDO, GIUSEPPE+5 more
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Editorial: Follicle-Stimulating Hormone: Fertility and Beyond [PDF]
Follicle-Stimulating Hormone: Fertility and Beyond Propagating life to the next generation is a hormone-dependent process relying on the individual wish to generate own progeny and resulting in maintenance of species. This Research Topic is dedicated to Follicle-Stimulating Hormone (FSH) and its receptor (FSHR) and their role in reproduction.
Simoni, Manuela+3 more
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Bioactive follicle-stimulating hormone [PDF]
Abstract Specific and sensitive in vitro bioassays suitable for measurement of follicle-stimulating hormone (FSH) in small quantities of serum and urine have recently been validated. Comparisons of bioassay (B-FSH) potencies with immunoassay (I-FSH) estimates and chromatofocusing patterns have facilitated new discoveries regarding the regulation of ...
Beitins, Inese Z., Padmanabhan, Vasantha
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Follicle-stimulating Hormone and Human Spermatogenesis [PDF]
The role of follicle-stimulating hormone (FSH) in the control of spermatogenesis is not well established in any species, including man. We studied the effect of an experimentally-induced, selective FSH deficiency on sperm production in normal men. After a 3-mo control period, five normal men received testosterone enanthate (T) 200 mg i. m.
W J Bremner+3 more
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Follicular and endocrine dose responses according to anti-Müllerian hormone levels in IVF patients treated with a novel human recombinant FSH (FE 999049) [PDF]
Objective: To study the association between serum anti-Mullerian hormone (AMH) levels and follicular development and endocrine responses induced by increasing doses (5.2-12.1 mu g/day) of a novel recombinant human FSH (rhFSH, FE 999049) in patients ...
Andersen, Anders Nyboe+9 more
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Activity of 3β-hydroxysteroid dehydrogenase associated with progesterone production in bovine granulosa cells cultured under different concentrations of serum, insulin-like growth factor I, and gonadotropin [PDF]
Three-β-hydroxysteroid dehydrogenase (3β-HSD) is the enzyme responsible for progesterone production. This study aimed to determine whether 3β-HSD activity can be shown to reflect progesterone production by granulosa cells cultured under different serum
Mihm Carmichael, Monika, Şimsek, Özkan
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Association of circulatory kisspeptin levels and hormonal interplay with male infertility: A cross-sectional study in Karachi, Pakistan [PDF]
Objectives: To determine the impact of Kisspeptin on male reproductive axis in a selected urban population.Methods: The cross-sectional study was conducted at the Sindh Institute of Reproductive Medicine in collaboration with Aga Khan University, Karachi,
Ahmed, Kaleem+4 more
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