Results 51 to 60 of about 685,855 (292)

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

The impact of infertility on serum heat shock protein 70, adropin and orexin levels in women: a case-control study

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Infertility is a major reproductive health issue affecting millions of women worldwide. Recent studies have highlighted the potential roles of metabolic and neuroendocrine peptides, including heat shock protein 70 (HSP70), adropin and orexin,
Noor Jassem Mohammed, Nagham Qasim Kadhim, Sabbar Rashid Lateef, Mohammed R. Abed Al-Joubory, Saif M. Hasan, Inaam Faisal Mohammed   +5 more
doaj   +1 more source

Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]

, 2010
Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel, Abel, M, Ellis, Peter J.I., Dunmore, B., Bauer, Johann W., Griffin, Darren K.   +5 more
core   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

DNA Sequence Analysis of Follicle-Stimulating Hormone (FSH) Gene and Follicle- Stimulating Hormone Receptor (FSHR) Gene in Madrasin Cattle with Ovarian Hypofunction [PDF]

, 2021
The research aims to determine the profile of the follicle-stimulating hormone (FSH) gene and follicle-stimulating hormone receptor (FSHR) gene polymorphism in Madrasin cattle with ovarian hypofunction. The method applied was carried out using laboratory
Budi Utomo, Erma Safitri
core   +1 more source

Effect of Bengkoang (Pachyrhizus erosus) Extract on Estrogen Receptor-?, Progesterone Receptor Expression, and Follicle-Stimulating Hormone Levels

Indonesian Journal of Obstetrics and Gynecology
Objective: Progesterone functions by inhibiting the release of Gonadotropin-Releasing Hormone (GnRH), which decreases Follicle-Stimulating Hormone (FSH) levels and converts them into hypoestrogens.
Suryanti, Mayasari Putri Ardela, Eka Frenty Hadiningsih, Sri Winarsih, Noorhamdani, Tatit Nurseta, Eviana Norahmawati   +6 more
doaj   +1 more source

Secondary Amenorrhea with Low Serum Luteinizing Hormone and Follicle-stimulating Hormone Caused by an Inhibin A- and Inhibin B-producing Granulosa Cell Tumor

Taiwanese Journal of Obstetrics & Gynecology, 2009
Objective: Here, we report a case of secondary amenorrhea with low serum luteinizing hormone and follicle-stimulating hormone levels due to an inhibin A- and inhibin B-producing granulosa cell tumor of the ovary.
Marzieh Agha-Hosseini, Ashraf Aleyaseen, Leili Safdarian, Ladan Kashani   +3 more
doaj   +1 more source

Follicle-stimulating Hormone and Human Spermatogenesis [PDF]

Journal of Clinical Investigation, 1981
The role of follicle-stimulating hormone (FSH) in the control of spermatogenesis is not well established in any species, including man. We studied the effect of an experimentally-induced, selective FSH deficiency on sperm production in normal men. After a 3-mo control period, five normal men received testosterone enanthate (T) 200 mg i. m.
W J, Bremner, A M, Matsumoto, A M, Sussman, C A, Paulsen   +3 more
openaire   +2 more sources

The effects of uterine artery embolisation and surgical treatment on ovarian function in women with uterine fibroids [PDF]

, 2010
Objective The aim of this study was to evaluate and compare both ovarian function and menstrual characteristics following uterine artery embolisation (UAE) and surgery. Design Subgroup of women from a randomised controlled trial.
D. Lyons, Murray, G. D., S. Rashid, Cooper, K., Rashid, S., Khaund, A., Lumsden, M.A., Moss, J.G., Murray, L.S., Lumsden, M. A., Moss, J. G., J. G. Moss, M. A. Lumsden, Lyons, D., K. Cooper, Murray, G.D., A. Khaund, Murray, L., L. S. Murray, G. D. Murray   +19 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source