Efficacy, safety and cost‐effectiveness of CAR‐T therapy
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Chest wall metastasis in postoperative thyroid cancer: a case report
Thyroid cancer is common in China. Thyroid adenocarcinoma metastases can be local or distal metastasis. Local metastasis presents as a hard and fixed lymph node in the neck, while distant metastases are found in the lung, skull, vertebrae, and pelvis ...
Jing-Jing Fan, Qiang Chen
doaj +1 more source
Background: Benign thyroid follicular tumors without histological evidence of carcinoma can metastasize. However, the pathogenesis of metastasis remains unclear. Here, the new proposed terminology, “non-invasive follicular thyroid neoplasm with papillary-
Yoo Jin Lee +14 more
doaj +1 more source
Regulatory harmonization: Evolution, globalization and future directions
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source
The clinical and morphological peculiarities of follicular thyroid carcinoma [PDF]
Introduction. Follicular thyroid cancer is manifest as a solitary nodule, incapsulate, round shape. In section the tumors have solid structures, whitish with small area of necrosis. During 28 years was undergo for surgery about 1394 of patients: 651 of
Motreac, Cristina
core +1 more source
POSSIBILITIES OF ULTRASOUND METHOD OF RESEARCH IN EARLY DIAGNOSTICS OF THYROID CARCINOMA
OBJECTIVE. This study evaluated the possibilities of ultrasound in diagnostics of early thyroid carcinoma. MATERIALS AND METHODS. The authors have compared the ultrasound results with data of postoperative histological examination in 106 patients with ...
A. M. Shulutko +6 more
doaj +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Follicular thyroid carcinoma (FTC) is a thyroid malignancy arising from follicular cells in which the diagnostic nuclear features of papillary thyroid carcinoma (PTC) are lacking.
Bartolazzi A +23 more
core +1 more source
Better Understanding in the Differentiation of Thyroid Follicular Adenoma, Follicular Carcinoma, and Follicular Variant of Papillary Carcinoma: A Retrospective Study [PDF]
Background. To evaluate the role of ultrasonography (US), US-guided fine-needle aspiration (USFNA) and intraoperative frozen section (FS) in follicular neoplasm. Methods.
육지현 +4 more
core +3 more sources
Distribution of histopathological types of thyroid tumors in 1999-2015 compared to 1966-1988 year period [PDF]
Background: The most common thyroid tumors originate from the epithelial follicular cells. Etiology involved in the development of thyroid carcinoma is multifactorial, including external influences and genetic predisposition.
Makazlieva Tanja +3 more
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