Results 111 to 120 of about 30,611 (293)

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

The First Description of the Hair Follicle Bulge by Franz von Leydig [PDF]

, 2011
Marlon R. Schneider, Schneider, Marlon R.   +1 more
core   +1 more source

The Function of Themis2 in B Cells

, 2015
Thymocyte-expressed molecule involved in selection 2 (Themis2) is the second member of the Themis family. Recently, the first member of the Themis family, Themis, has been reported to be part of the TCR signalling cascade and its deletion severely ...
Hartweger, H
core  

Concentrations of sex steroids in fluid from human antral follicles are dynamic and characterize transition from follicular recruitment to dominance

Objective: To study the dynamic changes of the human intrafollicular concentrations of all sex steroid hormones throughout the natural menstrual cycle using liquid chromatography-tandem mass spectrometry. Design: Observational Study. Subjects: Follicular
Mamsen, Linn Salto, Hay-Schmidt, Anders, Zheng, Mengxue, Styrishave, Bjarne, Andersen, Claus Yding, Johannsen, Malene Louise   +5 more
core   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Dynamic expression and functional analysis of circRNA in granulosa cells during follicular development in chicken

, 2019
Background Circular RNA (circRNA) is a type of noncoding RNA involved in a variety of biological processes, especially in post-transcriptional regulation. The granulosa cells of follicles play a determining role in ovarian development.
Xuemei Yin, Tao Zhang, Tingting Li, Pengfei Wu, Genxi Zhang, Lan Chen, Fuxiang Chen, Jinyu Wang, Manman Shen, Qiuhong Lou   +9 more
core   +1 more source

From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics

Advanced Science, EarlyView.
Mechanical properties of the oocyte are increasingly recognized as critical determinants of meiotic success and developmental potential. How actomyosin remodeling controls oocyte mechanics, how these properties are altered in pathological conditions, and how they could serve as markers in reproductive medicine are examined.
Anastasia Shihabi, Rose Bulteau, Lucie Barbier, Marie‐Emilie Terret   +3 more
wiley   +1 more source

Biophysical Characteristics of Human Follicular Fluid Prior To and After Low Temperature Preservation

, 2008
В работе исследованы основные биофизические параметры фолликулярной жидкости человека до и после действия низких температур. Показано незначительное влияние криоконсервирования на осмотическое давление, рН, плотность фолликулярной жидкости и увеличение ...
Липина, О.В., Тодоров, П., Чеканова, В.В., Тодрин, А.Ф., Чуб, Н.Н., Нипот, Е.Е., Горобченко, О.А., Пиняев, В.И.   +7 more
core  

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source