Non-invasive biomarkers in assisted reproductive technologies, current evidence, clinical utility and future perspectives. [PDF]
Zikopoulos A +9 more
europepmc +1 more source
Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang +6 more
wiley +1 more source
Development and validation of a prediction model for premature progesterone elevation during early-follicular phase long-acting GnRH-a long protocol. [PDF]
Ye T, Fan W, Du L, Li J, Kong H.
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Ovarian Collagen Regulates Granulosa Cell Proliferation Through Persistent Activation of the ERK1/2 Pathway in the Chinese Soft-Shelled Turtle (<i>Pelodiscus sinensis</i>). [PDF]
Han X +6 more
europepmc +1 more source
Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen +23 more
wiley +1 more source
Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su +7 more
wiley +1 more source
Dynamic Remodeling of Oocyte-Granulosa Cell Communication During Bovine Folliculogenesis Revealed by Transcriptomic Meta-Analyses. [PDF]
Monferini N +6 more
europepmc +1 more source

