Recent Advances in Top‐Down Proteomics for Single‐Cell Research
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
From a stem-cell-centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization. [PDF]
Jiang Z, Xu Y, Lou Y.
europepmc +1 more source
Phenotypic variation in functional traits underpins responses to environmental gradients, influencing thermoregulation, energy balance, and long‐term persistence under climate extremes. Climate change is altering these gradients globally, yet in species that have already disappeared from much of their range, adaptive phenotypes may have also been lost,
Jack Bilby +4 more
wiley +1 more source
Follicular fluid SCUBE1 as a novel angiogenesis-associated biomarker in women undergoing ART: a pilot study reflecting the follicular vascular microenvironment. [PDF]
Kizildemir YZ +8 more
europepmc +1 more source
Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs +5 more
wiley +1 more source
Hormonal Stabilization of the Bone-Metabolic Environment: Implications for Anterior Cruciate Ligament Integrity and Bone-Graft Integration. [PDF]
Koren A, Koren L.
europepmc +1 more source
Mammalian Osteoderm Ultrastructure in the Armored Acomys Spiny Mouse Tail
The ultrastructure of armored platelets – termed osteoderms – in the tail skin of Acomys cahirinus spiny mice is characterized using 2D and 3D microscopy methods. The imbricated structure is composed of calcium phosphate biomineral and has select structural elements that are bone‐like and tooth‐like in nature.
Joseph Deering +2 more
wiley +1 more source
Menstrual cycle does not change sagittal plane segments coordination variability during deadlift, a nonlinear dynamical analysis approach. [PDF]
Abbasi A +3 more
europepmc +1 more source
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida +7 more
wiley +1 more source
Extracellular vesicles in bovine reproduction: their journey from gametogenesis to pregnancy. [PDF]
Cajas YN +8 more
europepmc +1 more source

