Results 41 to 50 of about 3,016,950 (290)

Gonadotropin-Releasing Hormone (GnRH) and Its Agonists in Bovine Reproduction I: Structure, Biosynthesis, Physiological Effects, and Its Role in Estrous Synchronization

Animals
GnRH is essential for the regulation of mammalian reproductive processes. It regulates the production and release of pituitary gonadotropins, thereby influencing steroidogenesis and gametogenesis.
Eman M. Hassanein, Zoltán Szelényi, Ottó Szenci   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Spatio-Temporal Gene Expression Profiling during In Vivo Early Ovarian Folliculogenesis: Integrated Transcriptomic Study and Molecular Signature of Early Follicular Growth. [PDF]

PLoS ONE, 2015
The successful achievement of early ovarian folliculogenesis is important for fertility and reproductive life span. This complex biological process requires the appropriate expression of numerous genes at each developmental stage, in each follicular ...
Agnes Bonnet, Bertrand Servin, Philippe Mulsant, Beatrice Mandon-Pepin   +3 more
doaj   +1 more source

Formation of the ovarian follicular antrum and follicular fluid

, 2010
The formation of the follicular antrum and follicular fluid has received scant attention from researchers, yet both are important processes in follicular development.
Rodgers, R., F. Irving-Rodgers, Helen, Irving-Rodgers, Helen F, Irving-Rodgers, H., Rodgers, Raymond, Rodgers, Raymond J, Irving-Rodgers, Helen, J. Rodgers, Raymond   +7 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

Lipid Metabolic Process Involved in Oocyte Maturation During Folliculogenesis

Frontiers in Cell and Developmental Biology, 2022
Oocyte maturation is a complex and dynamic process regulated by the coordination of ovarian cells and numerous extraovarian signals. From mammal studies, it is learnt that lipid metabolism provides sufficient energy for morphological and cellular events ...
Tao Liu, Tao Liu, Tao Liu, Tao Liu, Tao Liu, Jiangxue Qu, Jiangxue Qu, Jiangxue Qu, Jiangxue Qu, Jiangxue Qu, Mengyuan Tian, Mengyuan Tian, Mengyuan Tian, Mengyuan Tian, Mengyuan Tian, Rui Yang, Rui Yang, Rui Yang, Rui Yang, Rui Yang, Xueling Song, Xueling Song, Xueling Song, Xueling Song, Xueling Song, Rong Li, Rong Li, Rong Li, Rong Li, Rong Li, Jie Yan, Jie Yan, Jie Yan, Jie Yan, Jie Yan, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao   +39 more
doaj   +1 more source

Influence of follicular dendritic cells on HIV dynamics [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000
In patients infected with human immunodeficiency virus type 1 (HIV-1), a large amount of virus is associated with follicular dendritic cells (FDCs) in lymphoid tissue. To assess the influence of FDCs on viral dynamics during antiretroviral therapy, we have developed a mathematical model for treatment of HIV-1 infection that ...
W S, Hlavacek, N I, Stilianakis, A S, Perelson   +2 more
openaire   +2 more sources

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source