Results 161 to 170 of about 1,288,138 (290)

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Metabolomic alterations in follicular fluid across female infertility conditions in IVF: a systematic review. [PDF]

J Assist Reprod Genet
D'Arco Correa L, Souza Peruzzato F, Rauh Muller YM.   +2 more
europepmc   +1 more source

The Role of High Cxcl11 Expression in Ovarian Dysfunction Through NF‐κB and AKT Pathways in a Thin Endometrium Mouse Model

iNew Medicine, EarlyView.
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang, Fei Tang, Zihan Meng, Yunxi Bao, Jujun Han, Xiaohua Jiang, Jianye Wang, Ying Wang, Zhaolian Wei   +8 more
wiley   +1 more source

Molecular signatures of oocyte viability identified by follicular fluid proteomics. [PDF]

Sci Rep
Kristensen SG, Subiran Adrados C, Elsner K, Cadenas J, Jensen LB, Tanvig MH, Greve VH, Colmorn LB, Marko-Varga G, Malm J, Gil J.   +10 more
europepmc   +1 more source

Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment

iNew Medicine, EarlyView.
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su, Fei Wang, Ting‐Hong Wei, Rui Lu, Wen‐Jun Huang, Xiang Zhang, Ling Yin, Jun Li   +7 more
wiley   +1 more source

Integrated follicular fluid multi-omics identifies steroidogenic dysregulation and a candidate SHBG-associated rescue framework in poor ovarian response. [PDF]

Front Endocrinol (Lausanne)
Zheng R, Jiao Y, Liu J, Yang W, Wang Z, Tang W, He Q, Wu Z, Xiang L.   +8 more
europepmc   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

IGF-II, IGFBP-4, -6, and -7, and HMGB1 show changes in follicular fluid in PCOS. [PDF]

Front Endocrinol (Lausanne)
Buia V, Catellani C, Croci S, Righi B, Morini D, Falbo AI, Nicoli A, De Fanti A, Belloni L, Aguzzoli L, Villani MT, Sartori C, Street ME.   +12 more
europepmc   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

Follicular Fluid Exosomes From Diminished Ovarian Reserve Patients Impair Granulosa Cell Function via miR-135a-5p-Mediated Suppression of BIRC5. [PDF]

Mol Reprod Dev
Ruan Z, Li Z, Shu J, Lin H, Li T, Feng Y, Wang X, Wang C, Wu Z, Huang Y, Xia M, Zhao X.   +11 more
europepmc   +1 more source