Results 191 to 200 of about 1,288,138 (290)

Organoid Coculture Models for Cancer Research and Immunotherapy

open access: yesMed Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang   +9 more
wiley   +1 more source

Clinical Effectiveness of Sialendoscopy in Radioactive Iodine‐induced Sialadenitis: A Systematic Review and Meta‐analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To systematically review and synthesize outcomes following sialendoscopy in patients with salivary gland dysfunction and a history of radioactive iodine (RAI). Data Sources A comprehensive search of Medline, Embase, and Cochrane Library was conducted from database inception through December 26, 2025.
Michal Kulasek   +2 more
wiley   +1 more source

Exposure profiles of legacy and emerging per- and polyfluoroalkyl substances in follicular fluid and their impacts on assisted reproductive outcomes: A multicenter study in China. [PDF]

open access: yesEco Environ Health
Lv H   +33 more
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

Bisphenol A Alternatives in Follicular Fluid: Novel Risk Factors for Ovarian Reserve Dysfunction. [PDF]

open access: yesACS Omega
Ren J   +8 more
europepmc   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida   +7 more
wiley   +1 more source

A Curious Case of Patterned Scarring Alopecia

open access: yes
JEADV Clinical Practice, EarlyView.
Jeta Buch   +3 more
wiley   +1 more source

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