Results 51 to 60 of about 85,330 (259)

Estradiol-mediated enhancement of the human ectocervical epithelial barrier correlates with desmoglein-1 expression in the follicular menstrual phase

open access: yesFrontiers in Endocrinology
BackgroundThe cervicovaginal epithelial barrier is crucial for defending the female reproductive tract against sexually transmitted infections. Hormones, specifically estradiol and progesterone, along with their respective receptor expressions, play an ...
Frideborg Bradley   +25 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

open access: yesAdvanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le   +4 more
wiley   +1 more source

The Effect of Menstrual Cycle Phases on Agility and Shoulder Endurance in Recreational Basketball Players

open access: yesOrthopaedic Journal of Sports Medicine
Background: Basketball, a widely played sport globally, has seen an increase in injury rates among players, particularly in ankle and knee joints, due to high-intensity movements.
Kamala Krishnan PT, MSc   +3 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Optimisation of the follicular phase in IVF/ICSI.

open access: yesFacts, views & vision in ObGyn, 2012
In reproductive medicine, the aim is to establish an optimal balance between cost-effectiveness, success rate and safety for the patient. In this thesis, a series of clinical studies are presented that all revolve around the optimisation of ovarian stimulation with GnRH antagonist co-treatment.
Blockeel, Christophe, Devroey, Paul
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Interaction of oestradiol and vasoactive factors in women with rs 2070744 polymorphism of endothelial NO-synthase gene

open access: yesЯкутский медицинский журнал
The aim of this study is the identification of interaction of oestradiol and vasoactive endothelial factors in women with polymorphism T-786C of endothelial nitric oxide synthase (eNOS) gene during follicular and luteal phase of the menstrual cycle ...
N. A. Bebyakova   +3 more
doaj   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

open access: yesAdvanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun   +6 more
wiley   +1 more source

Effect of short follicular phase with follicular maturity on conception outcome.

open access: yesClinical and experimental obstetrics & gynecology, 2005
To determine if a short follicular phase despite attaining a mature follicle is associated with a lower pregnancy rate. Furthermore the study would determine if delaying the maturation of the follicle by the use of ethinyl estradiol could improve the pregnancy rate.The clinical and viable pregnancy rates of 32 infertile patients were matched to 32 ...
J H, Check   +3 more
openaire   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

open access: yesAdvanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr   +19 more
wiley   +1 more source

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