Results 71 to 80 of about 7,109,986 (349)

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Virus-Like Particle-Mediated Vaccination against Interleukin-13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis [PDF]

, 2020
Virus-like particle (VLP)-based anti-infective prophylactic vaccination has been established in clinical use. Although validated in proof-of-concept clinical trials in humans, no VLP-based therapeutic vaccination against self-proteins to modulate chronic
Foerster, John, Molęda, Aleksandra
core   +2 more sources

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

The Effect of Menstrual Cycle and 6% ‍‍Carbohydrate Beverage Consumption on Maximal Physical Performance in Active Women

پزشکی بالینی ابن سینا, 2014
Introduction & Objective: Women during their lifetime experience a variety of physiological changes that can affect their physiological capacity to perform exercise and induce reduction in achieving the benefits of training.
Samavati Sharif, Sara Hojjati, Salman Vojdani, Somayeh Kasharafi Fard   +3 more
doaj  

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Association of brown adipose tissue activity with circulating sex hormones and fibroblast growth factor 21 in the follicular and luteal phases in young women

Journal of Physiological Anthropology
Background Thermogenesis is influenced by fluctuations in sex hormones during the menstrual cycle in premenopausal women. The thermogenic activity and mass of brown adipose tissue (BAT) are regulated by endocrine factors, including sex hormones and ...
Hirokazu Taniguchi, Yuka Hashimoto, Narumi Dowaki, Shinsuke Nirengi   +3 more
doaj   +1 more source

The value of automated follicle volume measurements in IVF/ICSI [PDF]

, 2014
Background/Aims: The objective of this literature study is to investigate the place of recent software technology sonography-based automated volume count (SonoAVC) for the automatic measurement of follicular volumes in IVF/ICSI.
Bracke, Victoria, De Sutter, Petra, Vandekerckhove, Frank   +2 more
core   +2 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Estradiol-mediated enhancement of the human ectocervical epithelial barrier correlates with desmoglein-1 expression in the follicular menstrual phase

Frontiers in Endocrinology
BackgroundThe cervicovaginal epithelial barrier is crucial for defending the female reproductive tract against sexually transmitted infections. Hormones, specifically estradiol and progesterone, along with their respective receptor expressions, play an ...
Frideborg Bradley, Alexandra Stern, Mathias Franzén Boger, Zaynab Mousavian, Olga Dethlefsen, Vilde Kaldhusdal, Julie Lajoie, Julie Lajoie, Kenneth Omollo, Kenneth Omollo, Sofia Bergström, Anna Månberg, Peter Nilsson, Joshua Kimani, Joshua Kimani, Joshua Kimani, Adam D. Burgener, Adam D. Burgener, Adam D. Burgener, Annelie Tjernlund, Christopher Sundling, Keith R. Fowke, Keith R. Fowke, Keith R. Fowke, Keith R. Fowke, Kristina Broliden   +25 more
doaj   +1 more source

Follicular and endocrine dose responses according to anti-Müllerian hormone levels in IVF patients treated with a novel human recombinant FSH (FE 999049) [PDF]

, 2015
Objective: To study the association between serum anti-Mullerian hormone (AMH) levels and follicular development and endocrine responses induced by increasing doses (5.2-12.1 mu g/day) of a novel recombinant human FSH (rhFSH, FE 999049) in patients ...
Andersen, Anders Nyboe, Arce, Joan-Carles, Barri, Pedro, Bosch, Ernesto, De Sutter, Petra, Fernández-Sánchez, Manuel, García-Velasco, Juan Antonio, Klein, Bjarke M, Mannaerts, Bernadette, Visnova, Hana   +9 more
core   +2 more sources