Perturbations in Lineage Specification of Granulosa and Theca Cells May Alter Corpus Luteum Formation and Function [PDF]
Anovulation is a major cause of infertility, and it is the major leading reproductive disorder in mammalian females. Without ovulation, an oocyte is not released from the ovarian follicle to be fertilized and a corpus luteum is not formed.
Abedel-Majed, Mohamed A. +3 more
core +1 more source
Ovarian function during hormonal contraception assessed by endocrine and sonographic markers: a systematic review [PDF]
This systematic review focuses on the literature evidence for residual ovarian function during treatment with hormonal contraceptives. We reviewed all papers which assessed residual ovarian activity during hormonal contraceptive use, using endocrine ...
Bastianelli, Carlo +5 more
core +1 more source
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F. +4 more
core +1 more source
Nevus sebaceus with syringocystadenoma papilliferum, prurigo nodularis, apocrine cystadenoma, basaloid follicular proliferation, and sebaceoma: case report and review of nevus sebaceus-associated conditions [PDF]
Nevus sebaceus is a benign skin hamartoma of congenital onset that grows during puberty, and in adulthood can develop secondary benign and malignant neoplasms.
Basu, Pallavi +3 more
core +1 more source
Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang +16 more
wiley +1 more source
Depending on the phase of the menstrual cycle, different values of running kinematic variables can be obtained. The aim of this study is to analyze whether there are changes in the kinematic variables in running throughout the menstrual cycle and to ...
Carolina Domínguez-Muñoz +5 more
doaj +1 more source
Effect of short follicular phase with follicular maturity on conception outcome.
To determine if a short follicular phase despite attaining a mature follicle is associated with a lower pregnancy rate. Furthermore the study would determine if delaying the maturation of the follicle by the use of ethinyl estradiol could improve the pregnancy rate.The clinical and viable pregnancy rates of 32 infertile patients were matched to 32 ...
J H, Check +3 more
openaire +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Classification of Jaw Bone Cysts and Necrosis via the Processing of Orthopantomograms [PDF]
The authors analyze the design of a method for automatized evaluation of parameters in orthopantomographic images capturing pathological tissues developed in human jaw bones.
Gescheidtova, E. +3 more
core +1 more source

